Detail Information for IndEnz0002018447
IED ID IndEnz0002018447
Enzyme Type ID protease018447
Protein Name CEP295 N-terminal-like protein
Differential display clone 8
KIAA1731 N-terminal like protein
Gene Name Cep295nl Ddc8 Kiaa1731nl
Organism Mus musculus (Mouse)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Glires (Rodents and rabbits) Rodentia Myomorpha (mice and others) Muroidea Muridae Murinae Mus Mus Mus musculus (Mouse)
Enzyme Sequence MQRDTERAAQLSPSSEDEALVLRQKPLEMPAQEEDSTTLQQWKARQLQRLAEELKAEWQEARLQQVRQAERLYLSHLLDEAAERSMGNDPSVHEQNQRRTAKHTRAKERNRAAFREERGRREEHPRQHPKSRKKAPCSERRSSAKARGPASGEKGKRRRVSSSKDHDGYQGPRVTRRVGVAKLNPFFDGDTDCMEDVQKEFFREGRRPSAKGTHNLRDQSLQGKTTALTQPLLHGPTCKQEAAAQEPPSKYNKNLWHKEIESTFEELFNMNRKLKKHLNLHLEQRLKADQNPDEQQSYSEIRSETFGTPREERTEEVETAEESGSPTEVETTEMWSKVNLKQILSDSEYPRYQQIAKYPLKSESLVPVKAGTSREQDDLLSLSPESGQEPPKSPLLEDESLKPYLQKQADSVASWMALRQKQKAELEQRRQKALLELTEHPNMSLEIHYKAELEEERRARRRMRLALLKSNSTGICALPPDRNNLSLDNGLLDEDKQNQMIRDLQQQILEQNKLHQEFLEKARKRLQEFQKSF
Enzyme Length 533
Uniprot Accession Number Q497N6
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Coiled coil (2); Compositional bias (3); Region (4); Sequence conflict (3)
Keywords Cell projection;Cilium;Coiled coil;Reference proteome
Interact With
Induction INDUCTION: Expression is moderately up-regulated 2 days after intracranial injury and increases at 4 and 7 days post-injury. {ECO:0000269|PubMed:16985004}.
Subcellular Location SUBCELLULAR LOCATION: Cell projection, cilium {ECO:0000269|PubMed:19706271}. Note=Colocalizes to the motile cilium of mature spermatozoa.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 18689890; 21267068; 24194600; 27626380;
Motif
Gene Encoded By
Mass 61,957
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda