| IED ID | IndEnz0002018450 |
| Enzyme Type ID | protease018450 |
| Protein Name |
Mitochondrial presequence protease EC 3.4.24.- |
| Gene Name | CYM1 FGRRES_05902 FGSG_05902 |
| Organism | Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) (Wheat head blight fungus) (Fusarium graminearum) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta sordariomyceta Sordariomycetes Hypocreomycetidae Hypocreales Nectriaceae Fusarium Fusarium sambucinum species complex Gibberella zeae (Wheat head blight fungus) (Fusarium graminearum) Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) (Wheat head blight fungus) (Fusarium graminearum) |
| Enzyme Sequence | MLRNAAAGARKAVTELSQFPKPGEKLHGFTLVRSKHVPELELTALHLQHDKTGADYLHIARDDSNNVFSIGFKTNPPDDTGIPHILEHTTLCGSEKYPIRDPFFKMLPRTLSNFMNAFTASDHTFYPFATTNAQDFKNLMSVYLDSTLHPLLKKSDFTQEGWRIGPENPLAEDEASKKLVFKGVVYNEMKGQMSDAGYLYYIRFHDHIFPDINNSGGDPQKITDLTYEQLQKFHAEHYHPSNAKVFTYGDMPLIDHLKQVDTQLQAFEKIQGDKQVHEPVTLNGPKEVTLYGPLDPLVDQDRQYKTSVSWIMGDTTDVLESFSLALLSTLLMDGYGSPLYRGLIEAGMGADWSPNAGYDSSAKKGIFSIGLTGVQEGDVPKLKEKVQQILRDARNKGFDKTKIDGSLHQLELSLKHKTANFGFSMLNRLKPKWFNGVDPFDSLAWNDTINGFQAKMAEGNYLEGLIDKYLLNDNTLTFTMAPSTTYGEDLVKEEQERLSTRIQAAIKEAGSEEKARKHFEKQEQELLVEQNKTNTEDLGCLPTVHVKDIPRSKEAVVVRDENANGTKIQWHEAPTNGLTYFRAINTLENLPDELRELVPLFTDSIMRLGTKDLNMEQLEDLIKLKTGGVSVGYHCTPSPTDFHAASEGIIFTGMALDHNVPVMFDIIQKLVLGTDFDSPEAALRIRQLLQASADGVVNDIASTGHRFAMGSAESGLTRSAWLRQQVSGLSQVQLVTSLASRPETDKLEDVISKLKQIQNLALVGGNLRTAITCGSESVAANGASLQNFVGNLSRDPLNLKNPSPRQLPKDSKTFYPLPYQVYYGGLSLPTTSYTSAEGAPLQILSQLLTHKHLHHEIREKGGAYGGGAYSRALDGLFGFYSYRDPNPQNTLSIMRNAGQWAVDKKWSDRDLEEAKISVFQGVDAPKSVNQEGMGRFLSGITEEMKQKKREQFLDVTKDQVREAAQRYLVDGLAKGEGRVAFLGEKQAWVDGEWQIREMDVKGAE |
| Enzyme Length | 1004 |
| Uniprot Accession Number | Q4IA56 |
| Absorption | |
| Active Site | ACT_SITE 87; /note=Proton acceptor; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.24.- |
| Enzyme Function | FUNCTION: ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides (By similarity). {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Metal binding (3); Transit peptide (1) |
| Keywords | Hydrolase;Metal-binding;Metalloprotease;Mitochondrion;Protease;Reference proteome;Transit peptide;Zinc |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 111,979 |
| Kinetics | |
| Metal Binding | METAL 84; /note=Zinc; catalytic; /evidence=ECO:0000250; METAL 88; /note=Zinc; catalytic; /evidence=ECO:0000250; METAL 188; /note=Zinc; catalytic; /evidence=ECO:0000250 |
| Rhea ID | |
| Cross Reference Brenda |