Detail Information for IndEnz0002018450
IED ID IndEnz0002018450
Enzyme Type ID protease018450
Protein Name Mitochondrial presequence protease
EC 3.4.24.-
Gene Name CYM1 FGRRES_05902 FGSG_05902
Organism Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) (Wheat head blight fungus) (Fusarium graminearum)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta sordariomyceta Sordariomycetes Hypocreomycetidae Hypocreales Nectriaceae Fusarium Fusarium sambucinum species complex Gibberella zeae (Wheat head blight fungus) (Fusarium graminearum) Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) (Wheat head blight fungus) (Fusarium graminearum)
Enzyme Sequence MLRNAAAGARKAVTELSQFPKPGEKLHGFTLVRSKHVPELELTALHLQHDKTGADYLHIARDDSNNVFSIGFKTNPPDDTGIPHILEHTTLCGSEKYPIRDPFFKMLPRTLSNFMNAFTASDHTFYPFATTNAQDFKNLMSVYLDSTLHPLLKKSDFTQEGWRIGPENPLAEDEASKKLVFKGVVYNEMKGQMSDAGYLYYIRFHDHIFPDINNSGGDPQKITDLTYEQLQKFHAEHYHPSNAKVFTYGDMPLIDHLKQVDTQLQAFEKIQGDKQVHEPVTLNGPKEVTLYGPLDPLVDQDRQYKTSVSWIMGDTTDVLESFSLALLSTLLMDGYGSPLYRGLIEAGMGADWSPNAGYDSSAKKGIFSIGLTGVQEGDVPKLKEKVQQILRDARNKGFDKTKIDGSLHQLELSLKHKTANFGFSMLNRLKPKWFNGVDPFDSLAWNDTINGFQAKMAEGNYLEGLIDKYLLNDNTLTFTMAPSTTYGEDLVKEEQERLSTRIQAAIKEAGSEEKARKHFEKQEQELLVEQNKTNTEDLGCLPTVHVKDIPRSKEAVVVRDENANGTKIQWHEAPTNGLTYFRAINTLENLPDELRELVPLFTDSIMRLGTKDLNMEQLEDLIKLKTGGVSVGYHCTPSPTDFHAASEGIIFTGMALDHNVPVMFDIIQKLVLGTDFDSPEAALRIRQLLQASADGVVNDIASTGHRFAMGSAESGLTRSAWLRQQVSGLSQVQLVTSLASRPETDKLEDVISKLKQIQNLALVGGNLRTAITCGSESVAANGASLQNFVGNLSRDPLNLKNPSPRQLPKDSKTFYPLPYQVYYGGLSLPTTSYTSAEGAPLQILSQLLTHKHLHHEIREKGGAYGGGAYSRALDGLFGFYSYRDPNPQNTLSIMRNAGQWAVDKKWSDRDLEEAKISVFQGVDAPKSVNQEGMGRFLSGITEEMKQKKREQFLDVTKDQVREAAQRYLVDGLAKGEGRVAFLGEKQAWVDGEWQIREMDVKGAE
Enzyme Length 1004
Uniprot Accession Number Q4IA56
Absorption
Active Site ACT_SITE 87; /note=Proton acceptor; /evidence=ECO:0000250
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.24.-
Enzyme Function FUNCTION: ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides (By similarity). {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Metal binding (3); Transit peptide (1)
Keywords Hydrolase;Metal-binding;Metalloprotease;Mitochondrion;Protease;Reference proteome;Transit peptide;Zinc
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 111,979
Kinetics
Metal Binding METAL 84; /note=Zinc; catalytic; /evidence=ECO:0000250; METAL 88; /note=Zinc; catalytic; /evidence=ECO:0000250; METAL 188; /note=Zinc; catalytic; /evidence=ECO:0000250
Rhea ID
Cross Reference Brenda