Detail Information for IndEnz0002018458
IED ID IndEnz0002018458
Enzyme Type ID protease018458
Protein Name Cysteine protease
EC 3.4.22.-
allergen Blo t 1
Gene Name
Organism Blomia tropicalis (Mite)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Chelicerata Arachnida Acari Acariformes Sarcoptiformes Astigmata Glycyphagoidea Echimyopodidae Blomia Blomia tropicalis (Mite)
Enzyme Sequence MKFLLVAALCALVAIGSCKPTREEIKTFEQFKKVFGKVYRNAEEEARREHHFKEQLKWVEEHNGIDGVEYAINEYSDMSEQEFSFHLSGGGLNFTYMKMEAAKEPLINTYGSLPQNFDWRQKARLTRIRQQGSCGSCWAFAAAGVAESLYSIQKQQSIELSEQELVDCTYNRYDSSYQCNGCGSGYSTEAFKYMIRTGLVEEENYPYNMRTQWCNPDVEGQRYHVSGYQQLRYQSSDEDVMYTIQQHGPVVIYMHGSNNYFRNLGNGVLRGVAYNDAYTDHAVILVGWGTVQGVDYWIIRNSWGTGWGNGGYGYVERGHNSLGINNFVTYATL
Enzyme Length 333
Uniprot Accession Number A1KXI0
Absorption
Active Site ACT_SITE 137; /evidence=ECO:0000250|UniProtKB:P00784; ACT_SITE 281; /evidence=ECO:0000250|UniProtKB:P00784; ACT_SITE 301; /evidence=ECO:0000250|UniProtKB:P00784
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.22.-
Enzyme Function FUNCTION: Cysteine protease. {ECO:0000250|UniProtKB:A5HII1}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (3); Beta strand (7); Chain (1); Disulfide bond (2); Glycosylation (1); Helix (13); Propeptide (1); Sequence conflict (7); Signal peptide (1); Turn (4)
Keywords 3D-structure;Allergen;Disulfide bond;Glycoprotein;Hydrolase;Protease;Signal;Thiol protease;Zymogen
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..18; /evidence=ECO:0000255
Structure 3D X-ray crystallography (1)
Cross Reference PDB 5JT8;
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 38,102
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda