| IED ID | IndEnz0002018458 |
| Enzyme Type ID | protease018458 |
| Protein Name |
Cysteine protease EC 3.4.22.- allergen Blo t 1 |
| Gene Name | |
| Organism | Blomia tropicalis (Mite) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Chelicerata Arachnida Acari Acariformes Sarcoptiformes Astigmata Glycyphagoidea Echimyopodidae Blomia Blomia tropicalis (Mite) |
| Enzyme Sequence | MKFLLVAALCALVAIGSCKPTREEIKTFEQFKKVFGKVYRNAEEEARREHHFKEQLKWVEEHNGIDGVEYAINEYSDMSEQEFSFHLSGGGLNFTYMKMEAAKEPLINTYGSLPQNFDWRQKARLTRIRQQGSCGSCWAFAAAGVAESLYSIQKQQSIELSEQELVDCTYNRYDSSYQCNGCGSGYSTEAFKYMIRTGLVEEENYPYNMRTQWCNPDVEGQRYHVSGYQQLRYQSSDEDVMYTIQQHGPVVIYMHGSNNYFRNLGNGVLRGVAYNDAYTDHAVILVGWGTVQGVDYWIIRNSWGTGWGNGGYGYVERGHNSLGINNFVTYATL |
| Enzyme Length | 333 |
| Uniprot Accession Number | A1KXI0 |
| Absorption | |
| Active Site | ACT_SITE 137; /evidence=ECO:0000250|UniProtKB:P00784; ACT_SITE 281; /evidence=ECO:0000250|UniProtKB:P00784; ACT_SITE 301; /evidence=ECO:0000250|UniProtKB:P00784 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.22.- |
| Enzyme Function | FUNCTION: Cysteine protease. {ECO:0000250|UniProtKB:A5HII1}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Beta strand (7); Chain (1); Disulfide bond (2); Glycosylation (1); Helix (13); Propeptide (1); Sequence conflict (7); Signal peptide (1); Turn (4) |
| Keywords | 3D-structure;Allergen;Disulfide bond;Glycoprotein;Hydrolase;Protease;Signal;Thiol protease;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..18; /evidence=ECO:0000255 |
| Structure 3D | X-ray crystallography (1) |
| Cross Reference PDB | 5JT8; |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 38,102 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |