Detail Information for IndEnz0002018482
IED ID IndEnz0002018482
Enzyme Type ID protease018482
Protein Name GDSL esterase/lipase At1g29660
EC 3.1.1.-
Apoplastic EDS1-dependent protein 3
Extracellular lipase At1g29660
Gene Name At1g29660 F15D2.21
Organism Arabidopsis thaliana (Mouse-ear cress)
Taxonomic Lineage cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress)
Enzyme Sequence MESYLRKWCLVSVWVLLLGLGFKVKAEPQVPCYFIFGDSLVDNGNNNRLRSIARADYFPYGIDFGGPTGRFSNGRTTVDVLTELLGFDNYIPAYSTVSGQEILQGVNYASAAAGIREETGAQLGQRITFSGQVENYKNTVAQVVEILGDEYTAADYLKRCIYSVGMGSNDYLNNYFMPQFYSTSRQYTPEQYADDLISRYRDQLNALYNYGARKFALVGIGAIGCSPNALAQGSQDGTTCVERINSANRIFNNRLISMVQQLNNAHSDASFTYINAYGAFQDIIANPSAYGFTNTNTACCGIGRNGGQLTCLPGEPPCLNRDEYVFWDAFHPSAAANTAIAKRSYNAQRSSDVYPIDISQLAQL
Enzyme Length 364
Uniprot Accession Number Q9C7N5
Absorption
Active Site ACT_SITE 39; /note=Nucleophile; /evidence=ECO:0000250|UniProtKB:Q09LX1; ACT_SITE 328; /note=Charge relay system; /evidence=ECO:0000250|UniProtKB:Q09LX1; ACT_SITE 331; /note=Charge relay system; /evidence=ECO:0000250|UniProtKB:Q09LX1
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.1.1.-
Enzyme Function FUNCTION: Involved in EDS1-dependent systemic acquired resistance, maybe in phloem-mediated long-distance signaling. {ECO:0000269|PubMed:24755512}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (3); Chain (1); Sequence conflict (2); Signal peptide (1)
Keywords Apoplast;Hydrolase;Lipid degradation;Lipid metabolism;Reference proteome;Secreted;Signal
Interact With
Induction INDUCTION: Down-regulated by drought (PubMed:19901554). Down-regulated by virulent or avirulent pathogen infection (PubMed:24755512). {ECO:0000269|PubMed:19901554, ECO:0000269|PubMed:24755512}.
Subcellular Location SUBCELLULAR LOCATION: Secreted, extracellular space, apoplast {ECO:0000269|PubMed:24755512}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..26; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 14617066; 15531708; 16299181; 18538804; 18552355; 18650403; 22442409; 28627464; 28840447;
Motif
Gene Encoded By
Mass 40,142
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda