| IED ID | IndEnz0002018493 |
| Enzyme Type ID | protease018493 |
| Protein Name |
Gamma-glutamyl peptidase 5 EC 3.4.19.- |
| Gene Name | GGP5 At2g23970 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress) |
| Enzyme Sequence | MVNEQKRFALFLATSDSTFVKKAYGGYFNVFVSTFGEDGEQWDLFRVIDGEFPDDKDLDKYDGFVISGSLNDAFGDDDWIVKLCSLCQKLDDMKKKVLGICFGHQILSRIKGGKVGRASRGLDMGLRSITMVTDAVKPGGYFGSQIPKSLAIIKCHQDEVLELPESATLLAYSDKYNVEMCSYGNHLLGIQGHPEYNKEILFEIIDRVVNLKLMEQDFADKAKATMENAEPDRKQWQTLCKNFLKGRSEQV |
| Enzyme Length | 251 |
| Uniprot Accession Number | O82225 |
| Absorption | |
| Active Site | ACT_SITE 101; /note=Nucleophile; /evidence=ECO:0000255|PROSITE-ProRule:PRU00605; ACT_SITE 193; /evidence=ECO:0000255|PROSITE-ProRule:PRU00605; ACT_SITE 195; /evidence=ECO:0000255|PROSITE-ProRule:PRU00605 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.19.- |
| Enzyme Function | FUNCTION: Involved in glucosinolate biosynthesis. Hydrolyzes the gamma-glutamyl peptide bond of several glutathione (GSH) conjugates to produce Cys-Gly conjugates related to glucosinolates. The gamma-Glu-Cys-Gly-GSH conjugates are the sulfur-donating molecule in glucosinolate biosynthesis. {ECO:0000250|UniProtKB:Q9M0A7}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | PATHWAY: Secondary metabolite biosynthesis. {ECO:0000305}. |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Domain (1) |
| Keywords | Cytoplasm;Hydrolase;Protease;Reference proteome |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9M0A7}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 16299181; 18775970; 20226671; 23858430; |
| Motif | |
| Gene Encoded By | |
| Mass | 28,312 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |