IED ID | IndEnz0002018539 |
Enzyme Type ID | protease018539 |
Protein Name |
Beta-barrel assembly-enhancing protease EC 3.4.-.- |
Gene Name | bepA yfgC STY2735 t0363 |
Organism | Salmonella typhi |
Taxonomic Lineage | cellular organisms Bacteria Proteobacteria Gammaproteobacteria Enterobacterales Enterobacteriaceae Salmonella Salmonella enterica (Salmonella choleraesuis) Salmonella enterica I Salmonella typhi |
Enzyme Sequence | MFRQLKKNLVATLIAALALGQVAPAFADPADTLPDMGTSAGSTLSIGQEMQMGDFYVRQLRGSAPLINDPLLVQYINALGMRLVSHADSVKTPFHFFLINNDEINAFAFFGGNVVLHSALFRYADNESQLASVMAHEISHVTQRHLARAMEDQKRSAPLTWVGALGSILLAMASPQAGMAALTGTLAGTRQGMISFTQQNEQEADRIGIQVLQRAGFDPQAMPSFLEKLLDQARYSTRPPEILLTHPLPESRLADARNRANQMRPVVVQSSADFYFAKARALGMYNSGRNQLTSDLLDQWSKGNVRQQHAAQYGRALQAMEASKYDEARKTLQPLLSAEPNNAWYLDLATDIDLGQKRANDAINRLKNARDLRVNPVLQLNLANAYLQGGQPKAAETILNRYTFSHKDDGNGWDLLAQAEAALNNRDQELAARAESYALAGRLDQAISLLSSASAQAKLGSQQQARYDARIDQLRQLQERFKPYTKM |
Enzyme Length | 487 |
Uniprot Accession Number | P66951 |
Absorption | |
Active Site | ACT_SITE 137; /evidence=ECO:0000255|HAMAP-Rule:MF_00997; ACT_SITE 205; /note=Proton donor; /evidence=ECO:0000255|HAMAP-Rule:MF_00997 |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | |
DNA Binding | |
EC Number | 3.4.-.- |
Enzyme Function | FUNCTION: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state. {ECO:0000255|HAMAP-Rule:MF_00997}. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Active site (2); Chain (1); Metal binding (3); Repeat (2); Signal peptide (1) |
Keywords | Hydrolase;Metal-binding;Metalloprotease;Periplasm;Protease;Repeat;Signal;TPR repeat;Zinc |
Interact With | |
Induction | |
Subcellular Location | SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00997}. |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | SIGNAL 1..27; /evidence=ECO:0000255|HAMAP-Rule:MF_00997 |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | - |
Motif | |
Gene Encoded By | |
Mass | 53,741 |
Kinetics | |
Metal Binding | METAL 136; /note=Zinc; catalytic; /evidence=ECO:0000255|HAMAP-Rule:MF_00997; METAL 140; /note=Zinc; catalytic; /evidence=ECO:0000255|HAMAP-Rule:MF_00997; METAL 201; /note=Zinc; catalytic; /evidence=ECO:0000255|HAMAP-Rule:MF_00997 |
Rhea ID | |
Cross Reference Brenda |