Detail Information for IndEnz0002018550
IED ID IndEnz0002018550
Enzyme Type ID protease018550
Protein Name Alpha-2-macroglobulin
Gene Name PD_0518
Organism Xylella fastidiosa (strain Temecula1 / ATCC 700964)
Taxonomic Lineage cellular organisms Bacteria Proteobacteria Gammaproteobacteria Xanthomonadales Xanthomonadaceae Xylella Xylella fastidiosa Xylella fastidiosa (strain Temecula1 / ATCC 700964)
Enzyme Sequence MRDRVAMMLRPLVRGWIPRAVLLLTVAFSFGCNRNHNGQLPQSSGEPVAVAKEPVKGFVLVRAYPDQHDGELALALEFSQPLAATQEFDTLVRLEQGSGNHDGGWSLSDDAKTLRYPYVEADKHYTVLISGDLLAATGSRLGKSRKEPVYTGELDPVVGFASRGSILPARGSRGVPVVSVNVPEVDVEFMRVREKALPAFLARYHKAGQRSSWELSNQGNSRKRLSELADPVYVTRFVLDGKKNERALTYLPIQNIRELREPGLYFAVMKPTGSFSDAFETAFFSVSNIGLHARAYKDKLFVHTASLRSGNPYKQVDLLVLDAKGETVLQGATDDNGNALLNYTLNAGHVLVSRNGRDISILPFNQPALDLSEFAVAGRENPWFDVFAWSGRDLYRPGEMLRISALLRDRDGKPVKPQPVFLRLKQPDGKTFRETRLQPAEQGYLEFTQKIPSDAPTGRWRVEFRTDPASKEAVQGLAVRVEEFLPERMKLELSSAQPVLRAKAPFTLTADAAYLYGAPAAGNRFTANLAVAVEQHPLDNMPGWFFGDATLQLPRGAKETIDITLGADGHLVHDIVLPEEAKPVSPMAVVVSGSVYESGGRPVTRSLKRVLWPADALVGVRPLFDVASGADANGMARFELTRVGVDGKPQSAKGLKATLVRELRDYHWRYSDGRWDYDFTRRFENKETRTVDISSSHTTTLSLPVEWGDYWLEVFDPVTGLTMRYPFRAGWSWGDDNRGLDARPDKVKLALDKTSYRAGDTLKVTITPPHPGKGLLLVESDKPLYVQAIDANPSTTLEIPVTADWERHDVYVTALVFRGGSASNNTTPARAVGEAYVPMQRKERRVAVGLVVPKQVRPAQSLPVTVSVPELAGKQAHVTISAVDAGILNITGFPVPDAAAHFFAQRRLSVDAYDIYGRVIESFEGGTGRLKFGGDMALPPLPQAKRPTARSQTVDLFSGAVKLDAKGNAHIQLPVPDFNGALRVSALVYSDTRYGQRDAETVVRAPILAEASMPRVMAPGDRSTVTVDVQNFTGKQGKFAVKVEGVGPLVVAEAGRSVTLGIDGKTTLNFPLRALEGNSVAQVRVRVEGNGSKAERHYDLPVRAVWPQGLRTQAHVLNVLAPIAFDPALAKGLMPDSVNARLSVSTLAPIPFASVLQGVFEYPYGCAEQTASKGYAALWLDDATIRSLGIQGVTPAQRLERLEGALGRLASLQTTNGHFSMWGGNSDVNPVLTPYIAGFLLDAKDAGFAVSDAVLQKALNRLSEDLLSGAHLFYGNDQSEALMFAHQAWSGYVLARVNRAPLGTLRTLYDNERGKAVSGLSLVHLGVALSLQGDRKRGEAAIEAGFAKSEGGRPEVFGDYGSVIRDNALMIALVRAHGLAKPAYEARVMALGRDLQARRRSGWLWLSTQEQVALAQLGRALLVDQKKQVSGTLYVGKQREDIAASRLIGRSFDAAALARGVRFVPQGDVPLYASFEVAGIPRQAPVSDDSQLLVVRRWYTVDGKPWTPGPLKEGQALIVRVSVTSKQNMPDALLTDLLPAGLEIENFNLGETRQWADVTVDGIALSERADAADIKHEEFRDDRYVAMLQLTGGRTANLFYLVRAVTPGSYNVPPSLVEDMYRPALRGTGRVAPAMVTVVQP
Enzyme Length 1641
Uniprot Accession Number Q87E11
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Protects the bacterial cell from host peptidases. {ECO:0000250|UniProtKB:P76578}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Cross-link (1); Lipidation (2); Signal peptide (1)
Keywords Cell membrane;Lipoprotein;Membrane;Palmitate;Protease inhibitor;Signal;Thioester bond
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..31; /evidence=ECO:0000255|PROSITE-ProRule:PRU00303
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 179,071
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda