Detail Information for IndEnz0002018552
IED ID IndEnz0002018552
Enzyme Type ID protease018552
Protein Name Three-finger toxin MicTx3
MCOR0100C
Three-finger toxin 3FTx-3
Gene Name
Organism Micrurus corallinus (Brazilian coral snake)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Sauropsida Sauria (diapsids) Lepidosauria (lepidosaurs) Squamata (squamates) Bifurcata (split-tongued squamates) Unidentata Episquamata Toxicofera Serpentes (snakes) Colubroidea Elapidae Elapinae Micrurus (coral snakes) Micrurus corallinus (Brazilian coral snake)
Enzyme Sequence MKTLLLTLVVVTIMCLDLGYTLVCYTNVLEPPGTLETCPDDFTCVKKWEGGGRRVTQYCSHACAIPASYEFVHCCQTDKCNG
Enzyme Length 82
Uniprot Accession Number C6JUP3
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Has been described to inhibit nicotinic acetylcholine receptor (nAChR) alpha-7/CHRNA7 subunits and to bind acetylcholine binding protein (AChBP) (Kd=29.5 nM) (PubMed:21214917). {ECO:0000269|PubMed:21214917}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Disulfide bond (4); Signal peptide (1)
Keywords Direct protein sequencing;Disulfide bond;Secreted;Signal;Toxin
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:19291316}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..21; /evidence=ECO:0000269|PubMed:21515432
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 9,070
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda