| IED ID | IndEnz0002018552 |
| Enzyme Type ID | protease018552 |
| Protein Name |
Three-finger toxin MicTx3 MCOR0100C Three-finger toxin 3FTx-3 |
| Gene Name | |
| Organism | Micrurus corallinus (Brazilian coral snake) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Sauropsida Sauria (diapsids) Lepidosauria (lepidosaurs) Squamata (squamates) Bifurcata (split-tongued squamates) Unidentata Episquamata Toxicofera Serpentes (snakes) Colubroidea Elapidae Elapinae Micrurus (coral snakes) Micrurus corallinus (Brazilian coral snake) |
| Enzyme Sequence | MKTLLLTLVVVTIMCLDLGYTLVCYTNVLEPPGTLETCPDDFTCVKKWEGGGRRVTQYCSHACAIPASYEFVHCCQTDKCNG |
| Enzyme Length | 82 |
| Uniprot Accession Number | C6JUP3 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Has been described to inhibit nicotinic acetylcholine receptor (nAChR) alpha-7/CHRNA7 subunits and to bind acetylcholine binding protein (AChBP) (Kd=29.5 nM) (PubMed:21214917). {ECO:0000269|PubMed:21214917}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Disulfide bond (4); Signal peptide (1) |
| Keywords | Direct protein sequencing;Disulfide bond;Secreted;Signal;Toxin |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:19291316}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..21; /evidence=ECO:0000269|PubMed:21515432 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 9,070 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |