| IED ID | IndEnz0002018564 |
| Enzyme Type ID | protease018564 |
| Protein Name |
Actinidain Actinidin EC 3.4.22.14 allergen Act c 1 |
| Gene Name | ACT1A CEY00_Acc12058 |
| Organism | Actinidia chinensis var. chinensis (Chinese soft-hair kiwi) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae asterids Ericales Actinidiaceae Actinidia Actinidia chinensis (Kiwi) (Yangtao) Actinidia chinensis var. chinensis (Chinese soft-hair kiwi) |
| Enzyme Sequence | MGLPKSFVSMSLLFFSTLLILSLAFNAKNLTQRTNDEVKAMYESWLIKYGKSYNSLGEWERRFEIFKETLRFIDEHNADTNRSYKVGLNQFADLTDEEFRSTYLGFTSGSNKTKVSNQYEPRVGQVLPSYVDWRSAGAVVDIKSQGECGGCWAFSAIATVEGINKIVTGVLISLSEQELIDCGRTQNTRGCNVGYITDGFQFIINNGGINTEENYPYTAQDGECNVDLQNEKYVTIDTYENVPYNNEWALQTAVTYQPVSVALDAAGDAFKHYSSGIFIGPCGTAIDHAVTIVGYGTEGGIDYWIVKNSWDTTWGEEGYMRILRNVGGAGTCGIATMPSYPVKYNNQNHPKSYSSLINPPAFSMSNDGPVGVDDGQRYSA |
| Enzyme Length | 380 |
| Uniprot Accession Number | P00785 |
| Absorption | |
| Active Site | ACT_SITE 151; ACT_SITE 288; ACT_SITE 308 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Specificity close to that of papain.; EC=3.4.22.14; |
| DNA Binding | |
| EC Number | 3.4.22.14 |
| Enzyme Function | FUNCTION: Cysteine protease responsible for the cleavage of kiwellin into kissper and KiTH. {ECO:0000269|PubMed:18442249}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Beta strand (7); Chain (1); Disulfide bond (3); Frameshift (2); Helix (9); Propeptide (1); Sequence conflict (37); Signal peptide (1); Turn (1) |
| Keywords | 3D-structure;Allergen;Direct protein sequencing;Disulfide bond;Hydrolase;Protease;Reference proteome;Signal;Thiol protease;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..24; /evidence=ECO:0000255 |
| Structure 3D | X-ray crystallography (2) |
| Cross Reference PDB | 1AEC; 2ACT; |
| Mapped Pubmed ID | 1606141; |
| Motif | |
| Gene Encoded By | |
| Mass | 42,098 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda | 3.4.22.14; |