IED ID | IndEnz0002018621 |
Enzyme Type ID | protease018621 |
Protein Name |
Aspartyl protease family protein 1 EC 3.4.23.- |
Gene Name | APF1 At2g17760 T17A5.8 |
Organism | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress) |
Enzyme Sequence | MVWYSSCRILFLGLLILLASSWVLDRCEGFGEFGFEFHHRFSDQVVGVLPGDGLPNRDSSKYYRVMAHRDRLIRGRRLANEDQSLVTFSDGNETVRVDALGFLHYANVTVGTPSDWFMVALDTGSDLFWLPCDCTNCVRELKAPGGSSLDLNIYSPNASSTSTKVPCNSTLCTRGDRCASPESDCPYQIRYLSNGTSSTGVLVEDVLHLVSNDKSSKAIPARVTFGCGQVQTGVFHDGAAPNGLFGLGLEDISVPSVLAKEGIAANSFSMCFGNDGAGRISFGDKGSVDQRETPLNIRQPHPTYNITVTKISVGGNTGDLEFDAVFDSGTSFTYLTDAAYTLISESFNSLALDKRYQTTDSELPFEYCYALSPNKDSFQYPAVNLTMKGGSSYPVYHPLVVIPMKDTDVYCLAIMKIEDISIIGQNFMTGYRVVFDREKLILGWKESDCYTGETSARTLPSNRSSSSARPPASSFDPEATNIPSQRPNTSTTSAAYSLSISLSLFFFSILAIL |
Enzyme Length | 513 |
Uniprot Accession Number | Q8VYV9 |
Absorption | |
Active Site | ACT_SITE 122; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094; ACT_SITE 327; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094 |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | |
DNA Binding | |
EC Number | 3.4.23.- |
Enzyme Function | FUNCTION: Aspartyl protease. Not able to cleave BAG6. {ECO:0000269|PubMed:26739014}. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Active site (2); Chain (1); Domain (1); Lipidation (1); Propeptide (1); Region (1); Signal peptide (1) |
Keywords | Aspartyl protease;Cell membrane;GPI-anchor;Glycoprotein;Hydrolase;Lipoprotein;Membrane;Protease;Reference proteome;Signal |
Interact With | |
Induction | |
Subcellular Location | SUBCELLULAR LOCATION: Cell membrane {ECO:0000255}; Lipid-anchor, GPI-anchor {ECO:0000255}. |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | SIGNAL 1..21; /evidence=ECO:0000255 |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | 12068095; 12805588; 14697270; 18650403; 21798944; 27247031; |
Motif | |
Gene Encoded By | |
Mass | 56,028 |
Kinetics | |
Metal Binding | |
Rhea ID | |
Cross Reference Brenda |