Detail Information for IndEnz0002018637
IED ID IndEnz0002018637
Enzyme Type ID protease018637
Protein Name Cystatin-A
Cystatin-alpha
Epidermal stefin
Epidermal thiol proteinase inhibitor
Gene Name Csta
Organism Rattus norvegicus (Rat)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Glires (Rodents and rabbits) Rodentia Myomorpha (mice and others) Muroidea Muridae Murinae Rattus Rattus norvegicus (Rat)
Enzyme Sequence MDPGTTGIVGGVSEAKPATPEIQEVADKVKRQLEEKTNEKYEKFKVVEYKSQVVAGQILFMKVDVGNGRFLHMKVLRGLSGDDDLKLLDYQTNKTKNDELTDF
Enzyme Length 103
Uniprot Accession Number P01039
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: This is an intracellular thiol proteinase inhibitor.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Modified residue (1); Motif (1); Site (1)
Keywords Acetylation;Cytoplasm;Direct protein sequencing;Protease inhibitor;Reference proteome;Thiol protease inhibitor
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cytoplasm.
Modified Residue MOD_RES 1; /note=N-acetylmethionine; /evidence=ECO:0000269|PubMed:6732797
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif MOTIF 52..56; /note=Secondary area of contact
Gene Encoded By
Mass 11,563
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda