IED ID | IndEnz0002018651 |
Enzyme Type ID | protease018651 |
Protein Name |
Gag polyprotein Pr53Gag Cleaved into: Matrix protein p16 MA ; Capsid protein p26 CA ; Nucleocapsid protein p13 NC |
Gene Name | gag |
Organism | Jembrana disease virus (JDV) |
Taxonomic Lineage | Viruses Riboviria Pararnavirae Artverviricota Revtraviricetes Ortervirales Retroviridae Orthoretrovirinae Lentivirus Jembrana disease virus (JDV) |
Enzyme Sequence | MKLSKLEKALKKVRVTPQRDDTYTIGNVLWAIRMCRLMGLDCCIDEATAAEVAILIGRFQSLDLQDSPLKGKDEKAILTTLKVLWSLLAGHHPENSDMAEKYWEAWTIRERESQKEEEGEITSIYPQLRKNFPAVSTSDGSPRYDPDLTKQLKIWADATEKHGVDHHAVNILGVITANLTQSEIRLLLQSTPQWRLDIQLIESKLNAREHAHRVWKESHPEAPKTDEIIGKGLTAAEQATLTTQECRDTYRQWVLEAALEVAQGKHDRPGPINIHQGPKEPYPEFVNKLVTALEGMAAPETTKQYLLDHLSVDHANEDCRAVLLPLGPSAPMERKLEACRAVGSSKQKMQFLAEAFAAINVKGDGEVQRCYGCGKPGHIRRDCKNQKCFKCGKPGHLQRNCKSKNGRRSSAPSGQRSGYHQEKTSVTPSAPPLVLD |
Enzyme Length | 436 |
Uniprot Accession Number | Q82850 |
Absorption | |
Active Site | |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | |
DNA Binding | |
EC Number | |
Enzyme Function | FUNCTION: Matrix protein p16 forms the outer shell of the core of the virus, lining the inner surface of the viral membrane. {ECO:0000250}.; FUNCTION: Capsid protein p26 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex. {ECO:0000250}.; FUNCTION: Nucleocapsid protein p13 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers (By similarity). {ECO:0000250}. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Chain (4); Compositional bias (1); Motif (1); Region (1); Site (2); Zinc finger (2) |
Keywords | Capsid protein;Host-virus interaction;Metal-binding;Reference proteome;Repeat;Ribosomal frameshifting;Viral budding;Viral budding via the host ESCRT complexes;Viral matrix protein;Viral nucleoprotein;Viral release from host cell;Virion;Virion maturation;Zinc;Zinc-finger |
Interact With | |
Induction | |
Subcellular Location | SUBCELLULAR LOCATION: [Matrix protein p16]: Virion {ECO:0000305}.; SUBCELLULAR LOCATION: [Capsid protein p26]: Virion {ECO:0000305}.; SUBCELLULAR LOCATION: [Nucleocapsid protein p13]: Virion {ECO:0000305}. |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | - |
Motif | MOTIF 428..431; /note=PTAP/PSAP motif |
Gene Encoded By | |
Mass | 48,785 |
Kinetics | |
Metal Binding | |
Rhea ID | |
Cross Reference Brenda |