Detail Information for IndEnz0002018783
IED ID IndEnz0002018783
Enzyme Type ID protease018783
Protein Name Probable Xaa-Pro aminopeptidase P
AMPP
Aminopeptidase P
EC 3.4.11.9
Aminoacylproline aminopeptidase
Prolidase
Gene Name ampp ATEG_08321
Organism Aspergillus terreus (strain NIH 2624 / FGSC A1156)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Circumdati Aspergillus terreus Aspergillus terreus (strain NIH 2624 / FGSC A1156)
Enzyme Sequence MLFSHPPIRLAWSSAFRSARQLPLSRPRFFSISVPRYAVDMETVDTTERLSRLRQLMKDHQVDVYIVPSEDSHQSEYIAPCDGRREFISGFSGSAGTAIVSLTKAALSTDGRYFNQASKQLDSNWVLLKRGVEGVQTWQEWTTEQAEGGKVVGVDPALITASGARSLSETLQKNGSSLKGIRPNLVDLVWGNDRPSPPREKVTVHPEKFAGKSFQDKISELRKELEKKKTAGFVISMLDEIAWLFNLRGTDIPYNPVFFSYAIITPTTAELYVDDDKLTPEVKAHLGQDVVVKPYDSIYADAEALSAARKQDAGDAAPKFLLSNKASWALSLSLGGEEQTEEVRSPIADAKAVKNDVELSGMRACHIRDGAALIEYFAWLENELVNKKTTLDEVDAADKLEQIRSKHELFAGLSFDTISSTGPNGAVIHYKPEKGSCSIIDPNAIYLCDSGAQFLDGTTDVTRTFHFGKPTELEKKAFTLVLKGMIALDSAVFPKGTSGFALDVLARQYLWQEGLDYLHGTGHGIGSYLNVHEGPMGIGTRVQYTEVPIAPGNVISNEPGFYEDGKFGIRIENVIMAREVQTPHKFGDRPWLGFEHVTMAPIGLNLIEPSLLSDSEIKWVNDYHAEVWEKTHHFFQNDERTRSWLQRETQPISK
Enzyme Length 654
Uniprot Accession Number Q0CDB3
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.; EC=3.4.11.9;
DNA Binding
EC Number 3.4.11.9
Enzyme Function FUNCTION: Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Metal binding (6)
Keywords Aminopeptidase;Hydrolase;Manganese;Metal-binding;Metalloprotease;Protease;Reference proteome
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 72,744
Kinetics
Metal Binding METAL 449; /note=Manganese 2; /evidence=ECO:0000250; METAL 460; /note=Manganese 1; /evidence=ECO:0000250; METAL 460; /note=Manganese 2; /evidence=ECO:0000250; METAL 558; /note=Manganese 1; /evidence=ECO:0000250; METAL 572; /note=Manganese 1; /evidence=ECO:0000250; METAL 572; /note=Manganese 2; /evidence=ECO:0000250
Rhea ID
Cross Reference Brenda