Detail Information for IndEnz0002018786
IED ID IndEnz0002018786
Enzyme Type ID protease018786
Protein Name Probable Xaa-Pro aminopeptidase P
AMPP
Aminopeptidase P
EC 3.4.11.9
Aminoacylproline aminopeptidase
Prolidase
Gene Name AMPP PABG_05506
Organism Paracoccidioides brasiliensis (strain Pb03)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Onygenales incertae sedis Paracoccidioides Paracoccidioides brasiliensis Paracoccidioides brasiliensis (strain Pb03)
Enzyme Sequence METVDTSQRLARLRELMKERNVDVYLVPSEDSHQSEYIAPCDGRREFISGFSGSAGCAIVSMTKAALSTDGRYFNQASKQLDNNWLLLKRGIESMPTWQEWTAEQLEGGKVVGVDPSLITASDARSLSETIKKSGGSLLGVQENLVDLVWGKDRPCRPSEKVTVHPVEFAGKSFEEKITDLRKELEKKKSAGFVVSMLDEVAWLFNLRGNDIPYNPVFFSYAIITPSTADLYIDEEKLSADVKKHLGDKVSLKPYTSIFEDAKALGQSAQAEVNGGASDPPRKFFISTKASWSLSLALGGANKVEEVRSPISDAKAIKNDTELEGMRACHIRDGAALTKYFAWLENELVNKKTVLNEVEASDKLEEIRSKQKNFVGLSFDTISSSGPNAAVVHYKAERKNCSIIDPEAVYLCDSGAQYLDGTTDTTRTLHFGEPTEKERKAYTLVLKGMIAIDTAIFPKGTTGFSLDTLARQFLWKEGLDYLHGTGHGVGSYLNVHEGPIGIGTRVQYSETPLSVGNVISDEPGYYEDGKFGIRIENIIMAREVKTTFSFGERPWLGFEHVTMTPLCRKLIDPSLLNDAEKKWINEYHSEVWEKTSGYFAEDELTRNWLKRETQPI
Enzyme Length 616
Uniprot Accession Number C0SCV1
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.; EC=3.4.11.9;
DNA Binding
EC Number 3.4.11.9
Enzyme Function FUNCTION: Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Metal binding (6)
Keywords Aminopeptidase;Hydrolase;Manganese;Metal-binding;Metalloprotease;Protease
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 68,630
Kinetics
Metal Binding METAL 413; /note=Manganese 2; /evidence=ECO:0000250; METAL 424; /note=Manganese 1; /evidence=ECO:0000250; METAL 424; /note=Manganese 2; /evidence=ECO:0000250; METAL 522; /note=Manganese 1; /evidence=ECO:0000250; METAL 536; /note=Manganese 1; /evidence=ECO:0000250; METAL 536; /note=Manganese 2; /evidence=ECO:0000250
Rhea ID
Cross Reference Brenda