| IED ID | IndEnz0002018819 |
| Enzyme Type ID | protease018819 |
| Protein Name |
Mitochondrial inner membrane protease ATP23 homolog EC 3.4.24.- Ku70-binding protein 3 XRCC6-binding protein 1 |
| Gene Name | ATP23 KUB3 XRCC6BP1 |
| Organism | Homo sapiens (Human) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Primates Haplorrhini Simiiformes Catarrhini Hominoidea (apes) Hominidae (great apes) Homininae Homo Homo sapiens (Human) |
| Enzyme Sequence | MAGAPDERRRGPAAGEQLQQQHVSCQVFPERLAQGNPQQGFFSSFFTSNQKCQLRLLKTLETNPYVKLLLDAMKHSGCAVNKDRHFSCEDCNGNVSGGFDASTSQIVLCQNNIHNQAHMNRVVTHELIHAFDHCRAHVDWFTNIRHLACSEVRAANLSGDCSLVNEIFRLHFGLKQHHQTCVRDRATLSILAVRNISKEVAKKAVDEVFESCFNDHEPFGRIPHNKTYARYAHRDFENRDRYYSNI |
| Enzyme Length | 246 |
| Uniprot Accession Number | Q9Y6H3 |
| Absorption | |
| Active Site | ACT_SITE 126; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.24.- |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Erroneous initiation (1); Metal binding (2); Natural variant (1) |
| Keywords | Hydrolase;Metal-binding;Metalloprotease;Protease;Reference proteome |
| Interact With | Q9NYB9-2; Q08043; Q9H1Y0; O95429; P41182; Q9NX04; Q96HB5; P33240; Q9H0L4; Q9UI47-2; Q9H596; Q14204; Q8IYI6; O75593; Q12951-2; O43559; Q8IVS8; Q96NT3-2; P52597; P49639; O43593; Q6P597-3; Q92876; Q9NRQ2; Q96I34; O75716; Q96PN8; Q15915 |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 23670597; |
| Motif | |
| Gene Encoded By | |
| Mass | 28,081 |
| Kinetics | |
| Metal Binding | METAL 125; /note=Divalent metal cation; catalytic; /evidence=ECO:0000250; METAL 129; /note=Divalent metal cation; catalytic; /evidence=ECO:0000250 |
| Rhea ID | |
| Cross Reference Brenda |