Detail Information for IndEnz0002018854
IED ID IndEnz0002018854
Enzyme Type ID protease018854
Protein Name Cathepsin Q
EC 3.4.22.-
Gene Name Ctsq Catq
Organism Rattus norvegicus (Rat)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Glires (Rodents and rabbits) Rodentia Myomorpha (mice and others) Muroidea Muridae Murinae Rattus Rattus norvegicus (Rat)
Enzyme Sequence MTPAVFLVILCLGVVPGASALDLSLDVQWQEWKIKYEKLYSPEEEVLKRVVWEENVKKIELHNRENSLGKNTYTMEINDFADMTDEEFKDMIIGFQLPVHNTEKRLWKRALGSFFPNSWNWRDALPKFVDWRNEGYVTRVRKQGGCSSCWAFPVTGAIEGQMFKKTGKLIPLSVQNLIDCSKPQGNRGCLWGNTYNAFQYVLHNGGLEAEATYPYERKEGVCRYNPKNSSAKITGFVVLPESEDVLMDAVATKGPIATGVHVISSSFRFYQKGVYHEPKCSSYVNHAVLVVGYGFEGNETDGNNYWLIKNSWGKRWGLRGYMKIAKDRNNHCAIASLAQYPTV
Enzyme Length 343
Uniprot Accession Number Q9QZE3
Absorption
Active Site ACT_SITE 149; /evidence=ECO:0000250; ACT_SITE 286; /evidence=ECO:0000250; ACT_SITE 310; /evidence=ECO:0000250
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.22.-
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (3); Chain (1); Disulfide bond (3); Glycosylation (2); Propeptide (1); Signal peptide (1)
Keywords Disulfide bond;Glycoprotein;Hydrolase;Lysosome;Protease;Reference proteome;Signal;Thiol protease;Zymogen
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Lysosome {ECO:0000305}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..20; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 12054558;
Motif
Gene Encoded By
Mass 39,052
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda