Detail Information for IndEnz0002018858
IED ID IndEnz0002018858
Enzyme Type ID protease018858
Protein Name Mucorpepsin
EC 3.4.23.23
Mucor rennin
Gene Name
Organism Rhizomucor pusillus
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Fungi incertae sedis Mucoromycota Mucoromycotina Mucoromycetes Mucorales (pin molds) Lichtheimiaceae Rhizomucor Rhizomucor pusillus
Enzyme Sequence MLFSKISSAILLTAASFALTSARPVSKQSDADDKLLALPLTSVNRKYSQTKHGQQAAEKLGGIKAFAEGDGSVDTPGLYDFDLEEYAIPVSIGTPGQDFYLLFDTGSSDTWVPHKGCDNSEGCVGKRFFDPSSSSTFKETDYNLNITYGTGGANGIYFRDSITVGGATVKQQTLAYVDNVSGPTAEQSPDSELFLDGMFGAAYPDNTAMEAEYGDTYNTVHVNLYKQGLISSPVFSVYMNTNDGGGQVVFGGANNTLLGGDIQYTDVLKSRGGYFFWDAPVTGVKIDGADAVSFDGAQAFTIDTGTNFFIAPSSFAEKVVKAALPDATESQQGYTVPCSKYQDSKTTFSLVLQKSGSSSDTIDVSVPISKMLLPVDKSGETCMFIVLPDGGNQFIVGNLFLRFFVNVYDFGKNRIGFAPLASGYENN
Enzyme Length 427
Uniprot Accession Number P09177
Absorption
Active Site ACT_SITE 104; ACT_SITE 303
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Hydrolysis of proteins, favoring hydrophobic residues at P1 and P1'. Clots milk. Does not accept Lys at P1, and hence does not activate trypsinogen.; EC=3.4.23.23;
DNA Binding
EC Number 3.4.23.23
Enzyme Function FUNCTION: This enzyme, capable of clotting milk is frequently used for cheese production.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Beta strand (26); Chain (1); Disulfide bond (2); Domain (1); Glycosylation (1); Helix (11); Propeptide (1); Sequence conflict (1); Signal peptide (1); Turn (4)
Keywords 3D-structure;Aspartyl protease;Direct protein sequencing;Disulfide bond;Glycoprotein;Hydrolase;Protease;Signal;Zymogen
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..22
Structure 3D X-ray crystallography (1)
Cross Reference PDB 1MPP;
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 45,646
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda