IED ID | IndEnz0002018858 |
Enzyme Type ID | protease018858 |
Protein Name |
Mucorpepsin EC 3.4.23.23 Mucor rennin |
Gene Name | |
Organism | Rhizomucor pusillus |
Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Fungi incertae sedis Mucoromycota Mucoromycotina Mucoromycetes Mucorales (pin molds) Lichtheimiaceae Rhizomucor Rhizomucor pusillus |
Enzyme Sequence | MLFSKISSAILLTAASFALTSARPVSKQSDADDKLLALPLTSVNRKYSQTKHGQQAAEKLGGIKAFAEGDGSVDTPGLYDFDLEEYAIPVSIGTPGQDFYLLFDTGSSDTWVPHKGCDNSEGCVGKRFFDPSSSSTFKETDYNLNITYGTGGANGIYFRDSITVGGATVKQQTLAYVDNVSGPTAEQSPDSELFLDGMFGAAYPDNTAMEAEYGDTYNTVHVNLYKQGLISSPVFSVYMNTNDGGGQVVFGGANNTLLGGDIQYTDVLKSRGGYFFWDAPVTGVKIDGADAVSFDGAQAFTIDTGTNFFIAPSSFAEKVVKAALPDATESQQGYTVPCSKYQDSKTTFSLVLQKSGSSSDTIDVSVPISKMLLPVDKSGETCMFIVLPDGGNQFIVGNLFLRFFVNVYDFGKNRIGFAPLASGYENN |
Enzyme Length | 427 |
Uniprot Accession Number | P09177 |
Absorption | |
Active Site | ACT_SITE 104; ACT_SITE 303 |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | CATALYTIC ACTIVITY: Reaction=Hydrolysis of proteins, favoring hydrophobic residues at P1 and P1'. Clots milk. Does not accept Lys at P1, and hence does not activate trypsinogen.; EC=3.4.23.23; |
DNA Binding | |
EC Number | 3.4.23.23 |
Enzyme Function | FUNCTION: This enzyme, capable of clotting milk is frequently used for cheese production. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Active site (2); Beta strand (26); Chain (1); Disulfide bond (2); Domain (1); Glycosylation (1); Helix (11); Propeptide (1); Sequence conflict (1); Signal peptide (1); Turn (4) |
Keywords | 3D-structure;Aspartyl protease;Direct protein sequencing;Disulfide bond;Glycoprotein;Hydrolase;Protease;Signal;Zymogen |
Interact With | |
Induction | |
Subcellular Location | |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | SIGNAL 1..22 |
Structure 3D | X-ray crystallography (1) |
Cross Reference PDB | 1MPP; |
Mapped Pubmed ID | - |
Motif | |
Gene Encoded By | |
Mass | 45,646 |
Kinetics | |
Metal Binding | |
Rhea ID | |
Cross Reference Brenda |