IED ID | IndEnz0002018866 |
Enzyme Type ID | protease018866 |
Protein Name |
Mitochondrial presequence protease EC 3.4.24.- |
Gene Name | CYM1 CAALFM_C306230WA CaO19.7410 |
Organism | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) |
Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Saccharomycotina (true yeasts) Saccharomycetes Saccharomycetales Debaryomycetaceae Candida/Lodderomyces clade Candida Candida albicans (Yeast) Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) |
Enzyme Sequence | MLKTRLKQSRAISRVVRRYACSHPISPNLDKYPVGLKLHGYEVTQTSPIPEFSLTAVSLKHTESGATHLHLDSPNDSNNVFSIAFKTNPPDNTGVPHILEHTTLCGSKKFPVRDPFFKMTNRSLSNFMNAMTGHDYTFYPFATTNSKDFENLMDVYLSSVFEPQLNHTDFLQEGWRIENQNVHDISSKLEFKGVVYNEMKGQYSNSAYYFYIKFLESIYPSLNNSGGDPKKIVDLSYEGLLEFHSKNYHPSNAKTFTYGKLPLEDSLSKISKYYESFEKKVSSVDVKQPIFSTDKSEIFDVTIPGPVDTMNGKETSEQYCTSITWNLGNPLDPNMQYDIFKWKILSSLLFDGHNSPFYQELIESGYGDDFSANTGLDSTTALLSFTVGLNYLTKQKVDNFNEKVMEIINNKIIPELSNEESSSYHGRIDAILHQIEIGFKRHKPDFGFGLLSSIVPSWVNGVDPIDTLQVEKILSHFKEDYKQNGLRIFKELLEKTLCNPHSQKFKFTMEPREDFTKQLVKDENLMIEKRVSELTEDNKKAIYEQNLELAKLQLEDQNTEVLPTLTIDDIPKRGDFYAIDLGQVNKKVVHERVVDTNGLVYANALKDISYLPTKLYKYLPLFNNCLTNLAGTENTPITELETKIQMLTGGITFSSKISTDPYNIEQLKLQYVLSGMALKEKSSSVYDLWLEILTTTKFDTSDEVLEKLSVLIKNMGQNQINNIADRGHSYAAAVSSSKLTPSKYISDIVSGLSQVQFVMELNSKLESEGKEYLAKEIIPILQEIQKYVLQGEFRYRLVGNQEIIVENEKLIEKFDKDISSNRPTLSLTVTDGLSALLNSFNYNHTSENVLVNLPFQVGYSSLGKIGSSYSSKDGASLQILSQLYSFKNLHSKIRESNGAYGGGLTYDGLNGTLNFYSYRDPNPVKSIQTFRDSLSYGLDANWNDKDLQEAKLRVFQSVDAPINISSQGASAFFENIDDYLRQERRENFLGTTLKDLRDVTEKYLVDNQNNLVTVIGDNEILNVDNKWQIRNFQV |
Enzyme Length | 1034 |
Uniprot Accession Number | Q5A301 |
Absorption | |
Active Site | ACT_SITE 100; /note=Proton acceptor; /evidence=ECO:0000250 |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | |
DNA Binding | |
EC Number | 3.4.24.- |
Enzyme Function | FUNCTION: ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides (By similarity). {ECO:0000250}. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Active site (1); Chain (1); Metal binding (3); Transit peptide (1) |
Keywords | Hydrolase;Metal-binding;Metalloprotease;Mitochondrion;Protease;Reference proteome;Transit peptide;Zinc |
Interact With | |
Induction | |
Subcellular Location | SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}. |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | - |
Motif | |
Gene Encoded By | |
Mass | 117,525 |
Kinetics | |
Metal Binding | METAL 97; /note=Zinc; catalytic; /evidence=ECO:0000250; METAL 101; /note=Zinc; catalytic; /evidence=ECO:0000250; METAL 198; /note=Zinc; catalytic; /evidence=ECO:0000250 |
Rhea ID | |
Cross Reference Brenda |