Detail Information for IndEnz0002018873
IED ID IndEnz0002018873
Enzyme Type ID protease018873
Protein Name Chymotrypsin BI
EC 3.4.21.1
Gene Name
Organism Penaeus vannamei (Whiteleg shrimp) (Litopenaeus vannamei)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Mandibulata Pancrustacea Crustacea Multicrustacea Malacostraca Eumalacostraca Eucarida Decapoda Dendrobranchiata Penaeoidea Penaeidae (penaeid shrimps) Penaeus Penaeus vannamei (Whiteleg shrimp) (Litopenaeus vannamei)
Enzyme Sequence MIGKLSLLLVCVAVASGNPAAGKPWHWKSPKPLVDPRIHVNATPRIVGGVEATPHSWPHQAALFIDDMYFCGGSLISSEWVLTAAHCMDGAGFVEVVLGAHNIRQNEASQVSITSTDFFTHENWNSWLLTNDIALIRLPSPVSLNSNIKTVKLPSSDVSVGTTVTPTGWGRPSDSASGISDVLRQVNVPVMTNADCDSVYGIVGDGVVCIDGTGGKSTCNGDSGGPLNLNGMTYGITSFGSSAGCEKGYPAAFTRVYYYLDWIQQKTGVTP
Enzyme Length 271
Uniprot Accession Number Q00871
Absorption
Active Site ACT_SITE 86; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 132; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 223; /note=Charge relay system; /evidence=ECO:0000250
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Preferential cleavage: Tyr-|-Xaa, Trp-|-Xaa, Phe-|-Xaa, Leu-|-Xaa.; EC=3.4.21.1; Evidence={ECO:0000255|PROSITE-ProRule:PRU10078, ECO:0000255|PROSITE-ProRule:PRU10079};
DNA Binding
EC Number 3.4.21.1
Enzyme Function FUNCTION: Serine protease with chymotryptic and collagenolytic activities.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (3); Chain (1); Disulfide bond (3); Domain (1); Propeptide (1); Signal peptide (1)
Keywords Collagen degradation;Direct protein sequencing;Disulfide bond;Hydrolase;Protease;Secreted;Serine protease;Signal;Zymogen
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted, extracellular space.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..15; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 28,685
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda