Detail Information for IndEnz0002018875
IED ID IndEnz0002018875
Enzyme Type ID protease018875
Protein Name Cyclolysin secretion/processing ATP-binding protein CyaB
EC 3.4.22.-
EC 7.6.2.-
Gene Name cyaB BN118_0469
Organism Bordetella pertussis (strain ATCC 9797 / DSM 5571 / NCTC 10739 / 18323)
Taxonomic Lineage cellular organisms Bacteria Proteobacteria Betaproteobacteria Burkholderiales Alcaligenaceae Bordetella Bordetella pertussis Bordetella pertussis (strain ATCC 9797 / DSM 5571 / NCTC 10739 / 18323)
Enzyme Sequence MTSPVAQCASVPDSGLLCLVMLARYHGLAADPEQLRHEFAEQAFCSETIQLAARRVGLKVRRHRPAPARLPRAPLPAIALDRQGGYFVLARFEPGADQAVLIQRPGQAPARLGQAEFEALWAGELLLCACAASPTQALARFDFSWFIPALVKHRHLIGEVLLISLVLQFISLLTPLFFQVVMDKVLVNNAMETLNVIAVGFLAAILFEALLTGIRTYLFAHTSSKLDVELGARLYAHLLRLPLAYFQARRVGDSVARVRELEHIRAFLTGNAVTVLLDVVFSVVFIAVMFFYSVKLTLVVLAALPCYFLLSLVLTPVLRRRLDVKFNRGAENQAFLVETVSGIDTVKSLAVEPQWQRNWDRQLAGYVAAGLSVANVAMLANTGVTLISRLVALGVLWVGATEVVAQRMTVGELVAFNMLSGHVTQPVIRLAQLWNDFQQTGVSMQRLGDILNCRTEVAGDKAQLPALRGSIELDRVSFRYRPDAADALRNVSLRIAPGEVVGVVGRSGSGKSTLTRLIQRMFVADRGRVLIDGHDIGIVDSASLRRQLGVVLQESTLFNRSVRDNIALTRPGASMHEVVAAARLAGAHEFICQLPEGYDTMLGENGVGLSGGQRQRIGIARALIHRPRVLILDEATSALDYESEHIIQRNMRDICDGRTVIIIAHRLSAVRCADRIVVMEGGEVAECGSHETLLAAGGLYARLQALQAGEAG
Enzyme Length 712
Uniprot Accession Number P0DKX6
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.22.-; 7.6.2.-
Enzyme Function FUNCTION: Involved in the export of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). {ECO:0000269|PubMed:2905265}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding NP_BIND 505..512; /note="ATP"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00362, ECO:0000255|PROSITE-ProRule:PRU00434"
Features Chain (1); Domain (3); Nucleotide binding (1); Sequence conflict (4); Transmembrane (6)
Keywords ATP-binding;Cell membrane;Cytolysis;Hemolysis;Hydrolase;Membrane;Nucleotide-binding;Protease;Thiol protease;Translocase;Transmembrane;Transmembrane helix;Transport
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 77,662
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda