Detail Information for IndEnz0002018883
IED ID IndEnz0002018883
Enzyme Type ID protease018883
Protein Name Flavastacin
EC 3.4.24.76
Gene Name
Organism Elizabethkingia meningoseptica (Chryseobacterium meningosepticum)
Taxonomic Lineage cellular organisms Bacteria FCB group Bacteroidetes/Chlorobi group Bacteroidetes Flavobacteriia Flavobacteriales Weeksellaceae Elizabethkingia Elizabethkingia meningoseptica (Chryseobacterium meningosepticum)
Enzyme Sequence MTRKLLILSGCLILALNSCKSDMETTPASSVDHTTTQLNGTTIHKLLINGAYTYVNEVNGEYFYADDITITAEQFNQLKRMANPDISTVERSTIVSSFIKTWPNATVYYTLPSQGSLSTQAYNTFLTNINKAFDMISSKTSVKFVQRTNQTEYITFTYSTGNSSPLGWVKNRVNGIKIYNTTYPAIIAHEIMHSMGIMHEQCRPDRDQYIIVDTNRAQDGTRHNFNLYNDYAGHGEFDFGSVMMYKSTDFAIDPNLPVMTKLDGSTFGKQRDGLSAGDYAGINHLYGPVNSTSATNGTYTLTTSLAGDKNIDITGSSTADGTDVILYSATTGNNQKFIFRKSEHGYFTIKSILDSTKVLTVRNNGTANGTAVELRTNADTDAQKWLLFNLGNEGFGFAPKNAPSLRLEVKDGLTTNLTPIVIGSTDQTLQPYTKQRFTLTKVN
Enzyme Length 443
Uniprot Accession Number Q47899
Absorption
Active Site ACT_SITE 190; /evidence=ECO:0000255|PROSITE-ProRule:PRU01211
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Hydrolyzes polypeptides on the amino-side of Asp in -Xaa-|-Asp-. Acts very slowly on -Xaa-|-Glu.; EC=3.4.24.76;
DNA Binding
EC Number 3.4.24.76
Enzyme Function FUNCTION: Zinc metallendopeptidase that cleaves preferentially on N-terminal side of aspartate-containing substrates.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Domain (2); Glycosylation (1); Metal binding (3); Propeptide (1); Signal peptide (1)
Keywords Direct protein sequencing;Glycoprotein;Hydrolase;Lectin;Metal-binding;Metalloprotease;Protease;Signal;Zinc;Zymogen
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification PTM: O-linked glycan consists of the Man, GlcNAc, GlcU, Glc, GlcU, Rha, Man heptasaccharide. {ECO:0000269|PubMed:7768917}.
Signal Peptide SIGNAL 1..15; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 48,957
Kinetics
Metal Binding METAL 189; /note=Zinc; via tele nitrogen; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU01211; METAL 193; /note=Zinc; via tele nitrogen; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU01211; METAL 199; /note=Zinc; via tele nitrogen; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU01211
Rhea ID
Cross Reference Brenda 3.4.24.76;