Detail Information for IndEnz0002018894
IED ID IndEnz0002018894
Enzyme Type ID protease018894
Protein Name Mitochondrial inner membrane protease ATP23
EC 3.4.24.-
Gene Name ATP23 PGUG_00463
Organism Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Saccharomycotina (true yeasts) Saccharomycetes Saccharomycetales Debaryomycetaceae Meyerozyma Meyerozyma guilliermondii (Yeast) (Candida guilliermondii) Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)
Enzyme Sequence MDVIYRSGTKLIWSSSMNDDRQTSSEDKLKGFEWWRRSLQYRTGLGLDEEEKLQFEHDYRVKNLPQKCDSCIEYRDWMFKYSPSVKFMMEHVQKLGGNLSSKNITCDMCDGMKGGGFHPEMGILLCSNWIKDKWQLEDILTHELVHAYDHLKFKVDLTNLKHHACTEIRASALSGECRILNEIKKTGLGDFGSKFQACVRRRAAISVSANPNCSSKEEAESVVNAVWESCFNDTRPFERVYR
Enzyme Length 242
Uniprot Accession Number A5DB08
Absorption
Active Site ACT_SITE 143; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.24.-
Enzyme Function FUNCTION: Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side. Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring (By similarity). {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Metal binding (2)
Keywords Hydrolase;Membrane;Metal-binding;Metalloprotease;Mitochondrion;Mitochondrion inner membrane;Protease;Reference proteome
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Associates loosely with the inner membrane. {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 28,042
Kinetics
Metal Binding METAL 142; /note=Divalent metal cation; catalytic; /evidence=ECO:0000250; METAL 146; /note=Divalent metal cation; catalytic; /evidence=ECO:0000250
Rhea ID
Cross Reference Brenda