Detail Information for IndEnz0002018972
IED ID IndEnz0002018972
Enzyme Type ID protease018972
Protein Name Syncephapepsin
EC 3.4.23.-
Gene Name SPSR
Organism Syncephalastrum racemosum (Filamentous fungus)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Fungi incertae sedis Mucoromycota Mucoromycotina Mucoromycetes Mucorales (pin molds) Syncephalastraceae Syncephalastrum Syncephalastrum racemosum (Filamentous fungus)
Enzyme Sequence MKFSLALLATVALATISQAAPVEKQVAGKPFQLVKNPHYQANATRAIFRAEKKYARHTAIPEQGKTIVKSAASGTGSVPMTDVDYDVEYYATVSVGTPAQSIKLDFDTGSSDLWFSSTLCTSCGSKSFDPTKSSTYKKVGKSWQISYGDGSSASGITATDNVELGGLKITGQTIELATRESSSFSSGAIDGILGLGFDTISTVAGTKTPVDNLISQNLISKPIFGVWLGKQSEGGGGEYVFGGYNTDHIDGSLTTVKVDNSQGWYGVTVSGLKVGSKSVASSFDGILDTGTTLLIFDQATGSKVAAAYGAKDNGDGTYTISCDQSKLQPLALTMGGKDFFVPADSLIYVKQGSQCIAGFGYSSMDFAIIGDTFLKNNYVVFNQGVPEVQIAPSKA
Enzyme Length 395
Uniprot Accession Number P81214
Absorption
Active Site ACT_SITE 107; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094; ACT_SITE 288; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.23.-
Enzyme Function FUNCTION: Hydrolysis of proteins with a broad specificity. Residues recognized to be cleaved were primarily those of trypsin and chymotrypsin and Lys was the most susceptible.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Disulfide bond (2); Domain (1); Propeptide (1); Signal peptide (1)
Keywords Aspartyl protease;Direct protein sequencing;Disulfide bond;Hydrolase;Protease;Signal;Zymogen
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..19; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 41,388
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda