Detail Information for IndEnz0002018977
IED ID IndEnz0002018977
Enzyme Type ID protease018977
Protein Name Major capsid protein
Gene product 8
Major head protein
Gene Name gene 8
Organism Escherichia phage N15 (Bacteriophage N15)
Taxonomic Lineage Viruses Duplodnaviria Heunggongvirae Uroviricota Caudoviricetes Caudovirales Siphoviridae (phages with long non-contractile tails) Ravinvirus Escherichia phage N15 (Bacteriophage N15)
Enzyme Sequence MSVYTTAQLLAVNEKKFKFDPLFLRIFFRETYPFSTEKVYLSQIPGLVNMALYVSPIVSGKVIRSRGGSTSEFTPGYVKPKHEVNPLMTLRRLPDEDPQNLADPVYRRRRIILQNMKDEELAIAQVEEKQAVAAVLSGKYTMTGEAFEPVEVDMGRSAGNNIVQAGAAAWSSRDKETYDPTDDIEAYALNASGVVNIIVFDPKGWALFRSFKAVKEKLDTRRGSNSELETALKDLGKAVSYKGMYGDVAIVVYSGQYIENDVKKNYLPDLTMVLGNTQARGLRTYGCILDADAQREGINASTRYPKNWVQTGDPAREFTMIQSAPLMLLADPDEFVSVKLA
Enzyme Length 341
Uniprot Accession Number O64322
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Assembles to form an icosahedral capsid with a T=7 symmetry. The icosahedral capsid is about 60 nm in diameter and composed of 415 major capsid proteins. The assembly is primed by the interaction between capsid assembly protease and portal dodecamer, and major capsid proteins assemble cooperatively to form the procapsid with the help of capsid scaffolding protein. Major capsid protein forms hexons and pentons of the icosahedron. Viral genomic DNA is packaged into the procapsid through the portal vertex. The packaging triggers a dramatic reconfiguration of the capsid shell. {ECO:0000250|UniProtKB:P03713}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Coiled coil (1)
Keywords Capsid protein;Coiled coil;Host cytoplasm;Late protein;Reference proteome;Virion
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Virion {ECO:0000255|HAMAP-Rule:MF_04133}. Host cytoplasm {ECO:0000255|HAMAP-Rule:MF_04133}. Note=Forms the capsid icosahedric shell. {ECO:0000255|HAMAP-Rule:MF_04133}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 38,026
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda