IED ID | IndEnz0002018985 |
Enzyme Type ID | protease018985 |
Protein Name |
Mitochondrial presequence protease EC 3.4.24.- |
Gene Name | CYM1 ADR184W |
Organism | Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) |
Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Saccharomycotina (true yeasts) Saccharomycetes Saccharomycetales Saccharomycetaceae Eremothecium Eremothecium gossypii (Yeast) (Ashbya gossypii) Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) |
Enzyme Sequence | MLRFQRTVPRVAIRRLANVYSEGAVLHGYKVRRAQEIPEMRMAAVELEHEMTGARHLHLEREDQNNVFSVGFRTPPPDATGVPHILEHTTLCGSQKYPVRDPFFKMLNRSLANFMNAMTAHDHTFYPFATTNQKDFANLRDLYLDATLRPLLRHADFLQEGWRLEHRDVGDASSELVFKGVVYNEMKGQVSNADYYFWIRFQEAIYPALHNSGGDPEHITDLSYEDLVAFHQNHYHPSNAKTFTYGNFPLRDTLRKLDDEFRGFGRRAIPQMHEKPLQLREAVSVEEPCQIDPMLPADKQCRTSMTWICGNPNDVYETFLLKILGSLLFDGHSSAFYKKLVEETGLAYELSVNTGVESQTAANFLTVGVQGCTDVGQVHKVIMETFTALLAQPFEKHRVEAILHQLELSKKDQKSDFGLQLLYGILPGWVNNTDPFDLLSLNSALQRFRADWDREGDGLFQRLLNKYVIGKPSFTFTMVGSSDFNQVKDQNEQSKLKAKVSSLTESDKEVIYKRGLHLQELQNSEQDLSKLPTLTTADIPHSSGHYFVSRDGPITTRQTDTNGITYIRMKRPLKGAIPYDAYPYIPLYSDGLMNIGTLLEDASAIEEQIRLHTGGISVSIGVHPNVETRLSELYLEISACALNSKTQYVFDIINKIMNETALSVRSEKMKVLIRAAASSFTSYAAENGHDLARLHTGAHFSQTQAIMEQTAGIEQVRHMNNLMSIIEKEAEFNTVLQNLEAMHRKIFVADGLEVMITTDNRQTSDVVKDQALKFIAGVQQSAGAESWLPEKYSRRALEKPYPALLQFPFQVHYTAQSTQGVSYTHPDGAHLQVLASLLTFKHLHREVREKGGAYGGGATYNATDGIFNFFSYRDPQPVRSLNIFRNAGKYVLNEARWTADDLNEAKLSIFQRVDAPISPSSEGLLQFRHNISDEQRDRRRQQLLKSTLDDVRRVADIYLVQPSPSQHMSAVVGPELPREVWSSQWPVIKV |
Enzyme Length | 990 |
Uniprot Accession Number | Q759T9 |
Absorption | |
Active Site | ACT_SITE 87; /note=Proton acceptor; /evidence=ECO:0000250 |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | |
DNA Binding | |
EC Number | 3.4.24.- |
Enzyme Function | FUNCTION: ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides (By similarity). {ECO:0000250}. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Active site (1); Chain (1); Metal binding (3); Transit peptide (1) |
Keywords | Hydrolase;Metal-binding;Metalloprotease;Mitochondrion;Protease;Reference proteome;Transit peptide;Zinc |
Interact With | |
Induction | |
Subcellular Location | SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}. |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | - |
Motif | |
Gene Encoded By | |
Mass | 112,270 |
Kinetics | |
Metal Binding | METAL 84; /note=Zinc; catalytic; /evidence=ECO:0000250; METAL 88; /note=Zinc; catalytic; /evidence=ECO:0000250; METAL 185; /note=Zinc; catalytic; /evidence=ECO:0000250 |
Rhea ID | |
Cross Reference Brenda |