IED ID | IndEnz0002018988 |
Enzyme Type ID | protease018988 |
Protein Name |
Dipeptidyl carboxypeptidase EC 3.4.15.5 Peptidyl-dipeptidase Dcp |
Gene Name | dcp STM1512 |
Organism | Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) |
Taxonomic Lineage | cellular organisms Bacteria Proteobacteria Gammaproteobacteria Enterobacterales Enterobacteriaceae Salmonella Salmonella enterica (Salmonella choleraesuis) Salmonella enterica I Salmonella typhimurium Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) |
Enzyme Sequence | MSTNPLLDQSMLPYQAPRFDRIKDCHYRPAFDEGVRQKRVEIEAIVNHPAAPDFTNTLLALEQSGALLSRVTSVFFAMTAAHTNDELQRLDEAFSAELAALSNDIYLNSALFARVDAVWQQRHSLGLDDESLRLVDVIHQRFVLAGAQLAEEDKARLKVLNTESATLMSQFNQRLLAASKAGGLAVDDAHCLAGLSPEEMTVAAEAAREKGLEERWFIPLLNTTQQPALATLRDRQTRENLFAASWTRAEKGDAHDTRAIVQRLVEIRRCQAKLLGFPNYAAWKMADQMAKTPQAALSFMRGIVPPARQRVLNEQAEIQNVIDGEQGGYTVQAWDWMFYAEQVRREKYALDEAQLKPYFALNTVLQEGVFWTANQLFGITFVERFDIPVYHPDVRVWEIFDSDGVGMALFYGDFFARDSKSGGAWMGNFVEQSTLNETRPVIYNVCNYQKPVDGQPALLLWDDVITLFHEFGHTLHGLFAVQRYATLSGTNTPRDFVEFPSQINEHWASHPRVFERYARHVDSGEKMPADLQERMRKASLFNKGYDMTELLGAALLDMRWHMLEESVAEQSVAEFEQQALAAEHLDLPAVPPRYRSSYFAHIFGGGYAAGYYAYLWTQMLADDGYQWFVEQGGLTRENGQRFRDAILARGNSTDLETLYSAWRGHEPHIDPMLQYRGLDR |
Enzyme Length | 680 |
Uniprot Accession Number | P27236 |
Absorption | |
Active Site | ACT_SITE 470; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095 |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | CATALYTIC ACTIVITY: Reaction=Hydrolysis of unblocked, C-terminal dipeptides from oligopeptides, with broad specificity. Does not hydrolyze bonds in which P1' is Pro, or both P1 and P1' are Gly.; EC=3.4.15.5; |
DNA Binding | |
EC Number | 3.4.15.5 |
Enzyme Function | FUNCTION: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides. {ECO:0000250|UniProtKB:P24171}. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Active site (1); Chain (1); Metal binding (3) |
Keywords | Carboxypeptidase;Cytoplasm;Direct protein sequencing;Hydrolase;Metal-binding;Metalloprotease;Protease;Reference proteome;Zinc |
Interact With | |
Induction | |
Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P24171}. |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | - |
Motif | |
Gene Encoded By | |
Mass | 77,261 |
Kinetics | |
Metal Binding | METAL 469; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095; METAL 473; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095; METAL 476; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095 |
Rhea ID | |
Cross Reference Brenda |