| IED ID |
IndEnz0002018999 |
| Enzyme Type ID |
protease018999 |
| Protein Name |
Cystatin-A1
|
| Gene Name |
cpiA DDB_G0291834 |
| Organism |
Dictyostelium discoideum (Slime mold) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Amoebozoa
Evosea
Eumycetozoa
Dictyostelia (dictyostelid cellular slime molds)
Dictyosteliales
Dictyosteliaceae
Dictyostelium
Dictyostelium discoideum (Slime mold)
|
| Enzyme Sequence |
MTLGGLKPEVHAANDEIRQVVAKVADELKSKLNTTEVEPVSYKTQLVAGTNYFIKVKTPAGFAHARVYKDLQQNHSVHSVKADGITEESEIVYF |
| Enzyme Length |
94 |
| Uniprot Accession Number |
Q65YR8 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Intracellular thiol proteinase inhibitor. Inhibits papain, but not cathepsin B. {ECO:0000269|PubMed:15255188}. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Motif (1); Site (1) |
| Keywords |
Cytoplasm;Protease inhibitor;Reference proteome;Thiol protease inhibitor |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:15255188}. |
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
|
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
16328887;
19482547;
20408569;
22120990;
|
| Motif |
MOTIF 45..49; /note=Secondary area of contact; /evidence=ECO:0000250 |
| Gene Encoded By |
|
| Mass |
10,401 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
|