Detail Information for IndEnz0002018999
IED ID IndEnz0002018999
Enzyme Type ID protease018999
Protein Name Cystatin-A1
Gene Name cpiA DDB_G0291834
Organism Dictyostelium discoideum (Slime mold)
Taxonomic Lineage cellular organisms Eukaryota Amoebozoa Evosea Eumycetozoa Dictyostelia (dictyostelid cellular slime molds) Dictyosteliales Dictyosteliaceae Dictyostelium Dictyostelium discoideum (Slime mold)
Enzyme Sequence MTLGGLKPEVHAANDEIRQVVAKVADELKSKLNTTEVEPVSYKTQLVAGTNYFIKVKTPAGFAHARVYKDLQQNHSVHSVKADGITEESEIVYF
Enzyme Length 94
Uniprot Accession Number Q65YR8
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Intracellular thiol proteinase inhibitor. Inhibits papain, but not cathepsin B. {ECO:0000269|PubMed:15255188}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Motif (1); Site (1)
Keywords Cytoplasm;Protease inhibitor;Reference proteome;Thiol protease inhibitor
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:15255188}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 16328887; 19482547; 20408569; 22120990;
Motif MOTIF 45..49; /note=Secondary area of contact; /evidence=ECO:0000250
Gene Encoded By
Mass 10,401
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda