| IED ID | IndEnz0002019011 |
| Enzyme Type ID | protease019011 |
| Protein Name |
Putative dipeptidase TRV_05564 EC 3.4.13.19 |
| Gene Name | TRV_05564 |
| Organism | Trichophyton verrucosum (strain HKI 0517) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Arthrodermataceae (dermatophytes) Trichophyton Trichophyton verrucosum (Cattle ringworm fungus) Trichophyton verrucosum (strain HKI 0517) |
| Enzyme Sequence | MAALFVSLLALTSLVPVQGAATVPQTDYAKRAERVLKSAPLIDGHNDLLYAIRRSTNDQIYDGKLPFETSLKGHTDLPRMRKGRMGGQFWSVFIACPSDPNAPINTPKFATRDTLEQIDVARRLVDKYSKDLMYCDNPGCAKRAFREGKIGSFIGIEGGHQVGSSIAALRQAFYAGARYMTLTHNCDNAWATAASTVRAGKPDLGMTDFGPALIKEMNRLGMLVDLSHVSHQTMRDVLKITKAPVIFSHSSAYEVSKHLRNVPDDVLKTVAKNNGVVMVTFVSSFVKVDDPDSADVNTVVKHIFHIAEVAGWDHVGLGGDYDGTTELPKGLEDVSKYPYLIEKVLEAGATEEQARKLVGENVLRVWTEVEQIAKKIQRSGVLPVEEVWKGRNGTALSERSTFIEGPAPLEYGCD |
| Enzyme Length | 414 |
| Uniprot Accession Number | D4DEJ7 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | BINDING 184; /note=Substrate; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073; BINDING 260; /note=Substrate; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073; BINDING 320; /note=Substrate; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073 |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid; Xref=Rhea:RHEA:48940, ChEBI:CHEBI:15377, ChEBI:CHEBI:59869, ChEBI:CHEBI:77460; EC=3.4.13.19; Evidence={ECO:0000255|PROSITE-ProRule:PRU10073}; |
| DNA Binding | |
| EC Number | 3.4.13.19 |
| Enzyme Function | FUNCTION: Hydrolyzes a wide range of dipeptides. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Binding site (3); Chain (1); Disulfide bond (1); Glycosylation (1); Metal binding (6); Signal peptide (1) |
| Keywords | Dipeptidase;Disulfide bond;Glycoprotein;Hydrolase;Metal-binding;Metalloprotease;Protease;Signal;Zinc |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..20; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 45,407 |
| Kinetics | |
| Metal Binding | METAL 45; /note=Zinc 1; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073; METAL 47; /note=Zinc 1; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073; METAL 157; /note=Zinc 1; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073; METAL 157; /note=Zinc 2; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073; METAL 228; /note=Zinc 2; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073; METAL 249; /note=Zinc 2; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073 |
| Rhea ID | RHEA:48940 |
| Cross Reference Brenda |