Detail Information for IndEnz0002019011
IED ID IndEnz0002019011
Enzyme Type ID protease019011
Protein Name Putative dipeptidase TRV_05564
EC 3.4.13.19
Gene Name TRV_05564
Organism Trichophyton verrucosum (strain HKI 0517)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Arthrodermataceae (dermatophytes) Trichophyton Trichophyton verrucosum (Cattle ringworm fungus) Trichophyton verrucosum (strain HKI 0517)
Enzyme Sequence MAALFVSLLALTSLVPVQGAATVPQTDYAKRAERVLKSAPLIDGHNDLLYAIRRSTNDQIYDGKLPFETSLKGHTDLPRMRKGRMGGQFWSVFIACPSDPNAPINTPKFATRDTLEQIDVARRLVDKYSKDLMYCDNPGCAKRAFREGKIGSFIGIEGGHQVGSSIAALRQAFYAGARYMTLTHNCDNAWATAASTVRAGKPDLGMTDFGPALIKEMNRLGMLVDLSHVSHQTMRDVLKITKAPVIFSHSSAYEVSKHLRNVPDDVLKTVAKNNGVVMVTFVSSFVKVDDPDSADVNTVVKHIFHIAEVAGWDHVGLGGDYDGTTELPKGLEDVSKYPYLIEKVLEAGATEEQARKLVGENVLRVWTEVEQIAKKIQRSGVLPVEEVWKGRNGTALSERSTFIEGPAPLEYGCD
Enzyme Length 414
Uniprot Accession Number D4DEJ7
Absorption
Active Site
Activity Regulation
Binding Site BINDING 184; /note=Substrate; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073; BINDING 260; /note=Substrate; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073; BINDING 320; /note=Substrate; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid; Xref=Rhea:RHEA:48940, ChEBI:CHEBI:15377, ChEBI:CHEBI:59869, ChEBI:CHEBI:77460; EC=3.4.13.19; Evidence={ECO:0000255|PROSITE-ProRule:PRU10073};
DNA Binding
EC Number 3.4.13.19
Enzyme Function FUNCTION: Hydrolyzes a wide range of dipeptides. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Binding site (3); Chain (1); Disulfide bond (1); Glycosylation (1); Metal binding (6); Signal peptide (1)
Keywords Dipeptidase;Disulfide bond;Glycoprotein;Hydrolase;Metal-binding;Metalloprotease;Protease;Signal;Zinc
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..20; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 45,407
Kinetics
Metal Binding METAL 45; /note=Zinc 1; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073; METAL 47; /note=Zinc 1; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073; METAL 157; /note=Zinc 1; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073; METAL 157; /note=Zinc 2; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073; METAL 228; /note=Zinc 2; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073; METAL 249; /note=Zinc 2; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073
Rhea ID RHEA:48940
Cross Reference Brenda