Detail Information for IndEnz0002019037
IED ID IndEnz0002019037
Enzyme Type ID protease019037
Protein Name Alpha-1-antiproteinase 2
Alpha-1-antitrypsin 2
Alpha-1-proteinase inhibitor 2
SPI2
Gene Name
Organism Equus caballus (Horse)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Laurasiatheria Perissodactyla (odd-toed ungulates) Equidae (horses) Equus Equus Equus caballus (Horse)
Enzyme Sequence MPSSVPWCLLLLAGLCCLVPSSLAEDLQGCAVQETHATAHDEEHLQEPAEHKIAPNLADFAFSLYRHVAHQSNTTNIFFSPVSIATAFALLSLGAKGDTHTQILEGLSFNLTELAEAQIHDGFQHLLNALNHSDNQLQLTTGNGLFIDESAKLLDKFLEDVKKLYHSEAFSINFRDTEEAKKQINDYVEKGTQGKIVDLVKDLDKDTVLALVNYIFFKGTWEKPFEPEYTTEQDFHVDEKTTVRVPMMHRLSSFDVQYSDTLSSWVLLLDYAGNATAFFILPDQGKLQHLEDTLTKGILARFLGNRHSSFVNVHLPKLSISGTYDLTSILPELGITKVFSRQADLSGITEEVPLTVSKALHKAVLTIDEKGTEAAGTTMWEIMPISLPPDLKFNRPFVLIIYDRNTKSPLFVGKVVDPTQK
Enzyme Length 421
Uniprot Accession Number P38029
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Inhibitor of serine proteases. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Glycosylation (3); Region (1); Sequence conflict (2); Signal peptide (1); Site (1)
Keywords Acute phase;Direct protein sequencing;Glycoprotein;Protease inhibitor;Reference proteome;Secreted;Serine protease inhibitor;Signal
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted.
Modified Residue
Post Translational Modification PTM: N-glycosylated with carbohydrates having biantennary side chains.
Signal Peptide SIGNAL 1..24; /evidence=ECO:0000269|PubMed:1772402
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 46,942
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda