IED ID | IndEnz0002019040 |
Enzyme Type ID | protease019040 |
Protein Name |
Disulfide bond formation protein D Disulfide oxidoreductase D Thiol-disulfide oxidoreductase D |
Gene Name | bdbD yvgV BSU33480 |
Organism | Bacillus subtilis (strain 168) |
Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Bacillales Bacillaceae Bacillus Bacillus subtilis group Bacillus subtilis Bacillus subtilis subsp. subtilis Bacillus subtilis (strain 168) |
Enzyme Sequence | MKKKQQSSAKFAVILTVVVVVLLAAIVIINNKTEQGNDAVSGQPSIKGQPVLGKDDAPVTVVEFGDYKCPSCKVFNSDIFPKIQKDFIDKGDVKFSFVNVMFHGKGSRLAALASEEVWKEDPDSFWDFHEKLFEKQPDTEQEWVTPGLLGDLAKSTTKIKPETLKENLDKETFASQVEKDSDLNQKMNIQATPTIYVNDKVIKNFADYDEIKETIEKELKGK |
Enzyme Length | 222 |
Uniprot Accession Number | O32218 |
Absorption | |
Active Site | |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | |
DNA Binding | |
EC Number | |
Enzyme Function | FUNCTION: Required for the stabilization, possibly via formation of a disulfide bond, of the obligatory competence protein ComGC. May be required for the stability of secreted proteins with disulfide bonds. Not required for sporulation. {ECO:0000269|PubMed:11744713}. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Beta strand (6); Chain (1); Disulfide bond (1); Domain (1); Helix (9); Mutagenesis (1); Signal peptide (1); Turn (2) |
Keywords | 3D-structure;Cell membrane;Competence;Disulfide bond;Membrane;Oxidoreductase;Redox-active center;Reference proteome;Signal |
Interact With | |
Induction | |
Subcellular Location | SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:20713508, ECO:0000269|PubMed:22882210}. Membrane raft {ECO:0000269|PubMed:20713508, ECO:0000269|PubMed:22882210}. Note=Present in detergent-resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts; these rafts include proteins involved in signaling, molecule trafficking and protein secretion. {ECO:0000269|PubMed:20713508, ECO:0000269|PubMed:22882210}. |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | SIGNAL 1..36; /evidence=ECO:0000255 |
Structure 3D | X-ray crystallography (4) |
Cross Reference PDB | 3EU3; 3EU4; 3GH9; 3GHA; |
Mapped Pubmed ID | 19535335; |
Motif | |
Gene Encoded By | |
Mass | 24,905 |
Kinetics | |
Metal Binding | |
Rhea ID | |
Cross Reference Brenda |