Detail Information for IndEnz0002019073
IED ID IndEnz0002019073
Enzyme Type ID protease019073
Protein Name Accessory gene regulator protein B
EC 3.4.-.-
Gene Name agrB SERP1490
Organism Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
Taxonomic Lineage cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Bacillales Staphylococcaceae Staphylococcus Staphylococcus epidermidis Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
Enzyme Sequence MKIIDKKIEQFAQYLQRKNNLDHIQFLKIRLGMQVLAINIEKSIVVYGLAIIFHTFFYTLLTHLSYFLIRRHAHGTHANSSLLCHIQNIIFFIIFPYLIIKLDINYFVLLSMALVGLIITILYAPAATKKQPIPRRLVKRKKILSIFLYCTIVVISLVTKEPVNKLILFGVILESLTLLPIFFPKEDINHGKHF
Enzyme Length 194
Uniprot Accession Number Q5HMY5
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.-.-
Enzyme Function FUNCTION: Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP). This quorum sensing system is responsible for the regulation of the expression of virulence factor genes. Involved in the proteolytic processing of AgrD, the precursor of AIP. {ECO:0000255|HAMAP-Rule:MF_00784}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Transmembrane (5)
Keywords Cell membrane;Hydrolase;Membrane;Protease;Quorum sensing;Reference proteome;Transmembrane;Transmembrane helix;Virulence
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00784}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00784}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 22,573
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda