Detail Information for IndEnz0002019102
IED ID IndEnz0002019102
Enzyme Type ID protease019102
Protein Name Putative cathepsin L 3
EC 3.4.22.15
Gene Name GSPATT00022199001
Organism Paramecium tetraurelia
Taxonomic Lineage cellular organisms Eukaryota Sar Alveolata Ciliophora Intramacronucleata Oligohymenophorea Peniculida Parameciidae Paramecium Paramecium tetraurelia
Enzyme Sequence MKQFLTAAIVTLLMTAGYYHLQEDDTNDFERWALKNNKFYTESEKLYRMEIYNSNKRMIEEHNQREDVTYQMGENQFMTLSHEEFVDLYLQKSDSSVNIMGASLPEVQLEGLGAVDWRNYTTVKEQGQCASGWAFSVSNSLEAWYAIRGFQKINASTQQIVDCDYNNTGCSGGYNAYAMEYVLRVGLVSSTNYPYVAKNQTCKQSRNGTYFINGYSFVGGSQSNLQYYLNNYPISVGVEASNWQFYRSGLFSNCSSNGTNHYALAVGFDSANNWIVQNSWGTQWGESGNIRLYPQNTCGILNYPYQVY
Enzyme Length 308
Uniprot Accession Number Q94715
Absorption
Active Site ACT_SITE 261; /evidence=ECO:0000250; ACT_SITE 278; /evidence=ECO:0000250
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Specificity close to that of papain. As compared to cathepsin B, cathepsin L exhibits higher activity toward protein substrates, but has little activity on Z-Arg-Arg-NHMec, and no peptidyl-dipeptidase activity.; EC=3.4.22.15;
DNA Binding
EC Number 3.4.22.15
Enzyme Function FUNCTION: May be involved in extracellular digestion.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Disulfide bond (2); Propeptide (1); Signal peptide (1); Site (1)
Keywords Disulfide bond;Hydrolase;Protease;Reference proteome;Secreted;Signal;Thiol protease;Zymogen
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..21; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 35,189
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda