Detail Information for IndEnz0002019148
IED ID IndEnz0002019148
Enzyme Type ID protease019148
Protein Name Probable Xaa-Pro aminopeptidase P
AMPP
Aminopeptidase P
EC 3.4.11.9
Aminoacylproline aminopeptidase
Prolidase
Gene Name AMPP GSTUM_00005237001
Organism Tuber melanosporum (strain Mel28) (Perigord black truffle)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina Pezizomycetes Pezizales Tuberaceae Tuber (truffles) Tuber melanosporum (Perigord truffle) Tuber melanosporum (strain Mel28) (Perigord black truffle)
Enzyme Sequence METVDTTSRLAKLRELMKRERVDVYVVPSEDAHSSEYICAADARRAFISGFTGSAGCAIVTQEKAALSTDGRYFNQAARQLDENWELLKQGLPDVPTWQEWVAQQAEGGKNVGVDATVITAQQAKSLETRIKKKGGTSLLGIPNNLIDEVWGADRPNRPNNPVMVLDEKYSGKEFPLKIEAVRKELENKKSPGFVVSMLDEIAWLFNLRGTDIPYNPVFFSYAFISPESTTLYIDSSKLDEKVIAHLGSAVKIRPYHEIFDEIDLLAQKLKVGQPETDSKASEDGGKWLVSNKTSWALSKALGGDDAIEVIRSPVEEEKAVKNDTEKEGMKRCHIRDGAALTEYFAWLEDELLKGTKIDEVQAADKLEQIRSRGENFMGLSFDTISSTGPNAAVIHYKPEAGNCSVIDPKAIYLCDSGAQYLDGTTDTTRTLHFGEPTDMERKSYTLVLKGMIALDRAIFPKGTSGFALDILARQFLWSEGLDYRHGTGHGVGSFLNVHEGPFGIGTRIQYSEVALSPGMFVSNEPGYYEDGSFGIRIENIIMVKEVKTSHSFGDRPYFGFERVTMVPMCRKLIDAGLLTPAETEWLNSYHAEVFEKTHGFFEKDSLASKWLKRETTPI
Enzyme Length 619
Uniprot Accession Number D5GAC6
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.; EC=3.4.11.9;
DNA Binding
EC Number 3.4.11.9
Enzyme Function FUNCTION: Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Metal binding (6)
Keywords Aminopeptidase;Hydrolase;Manganese;Metal-binding;Metalloprotease;Protease;Reference proteome
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 68,925
Kinetics
Metal Binding METAL 416; /note=Manganese 2; /evidence=ECO:0000250; METAL 427; /note=Manganese 1; /evidence=ECO:0000250; METAL 427; /note=Manganese 2; /evidence=ECO:0000250; METAL 525; /note=Manganese 1; /evidence=ECO:0000250; METAL 539; /note=Manganese 1; /evidence=ECO:0000250; METAL 539; /note=Manganese 2; /evidence=ECO:0000250
Rhea ID
Cross Reference Brenda