Detail Information for IndEnz0002019243
IED ID IndEnz0002019243
Enzyme Type ID protease019243
Protein Name Ecotin
Gene Name eco ECUMN_2545
Organism Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)
Taxonomic Lineage cellular organisms Bacteria Proteobacteria Gammaproteobacteria Enterobacterales Enterobacteriaceae Escherichia Escherichia coli Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)
Enzyme Sequence MKTILPAVLFAAFATTSAWAAESVQPLEKIAPYPQAEKGMKRQVIQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLESKTLEGWGYDYYVFDKVSSPVSTMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDNVDVKYRVWKAEEKIDNAVVR
Enzyme Length 162
Uniprot Accession Number B7N5H1
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases. {ECO:0000255|HAMAP-Rule:MF_00706}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Disulfide bond (1); Signal peptide (1); Site (1)
Keywords Disulfide bond;Periplasm;Protease inhibitor;Serine protease inhibitor;Signal
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00706}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..20; /evidence=ECO:0000255|HAMAP-Rule:MF_00706
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 18,165
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda