Detail Information for IndEnz0002019287
IED ID IndEnz0002019287
Enzyme Type ID protease019287
Protein Name Carboxyl-terminal-processing protease
EC 3.4.21.102
CtpA
Gene Name ctpA SYNPCC7002_A0843
Organism Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum)
Taxonomic Lineage cellular organisms Bacteria Terrabacteria group Cyanobacteria/Melainabacteria group Cyanobacteria Synechococcales Synechococcaceae Synechococcus unclassified Synechococcus Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum)
Enzyme Sequence MLRKRLQAGLCSLLLVLVLVFGPMERAIAFTDEQDLLLQAWRYVSQAYVDETFNHQNWWLIRQKFLKRPLKTRDEAYEAVGEMLALLDDPYTRLLRPEQYRSLKVSTSGELSGVGLQINVNPEVDVLEVILPLPGSPAEAAGIEAKDQILAIDGIDTRNIGLEEAAARMRGKKGSTVSLTVKSPKTDTVRTVKVTRDTIALNPVYDKLDEKNGEKVGYIRLNQFSANAKTEIIKSLNQLQKQGADRYVLDLRNNPGGLLQAGIEIARLWLDQETIVYTVNRQGIFESYSAVGQPLTDAPLVVLVNQATASASEILAGALQDNGRAMLVGEKTFGKGLIQSLFELPDGAGMAVTVAKYETPLHHDINKLGIMPDEVVPQEPIGYAMMGSETDLQYQAALDLLTQDQAIAQISQAS
Enzyme Length 414
Uniprot Accession Number P42784
Absorption
Active Site ACT_SITE 310; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 321; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 335; /note=Charge relay system; /evidence=ECO:0000250
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=The enzyme shows specific recognition of a C-terminal tripeptide, Xaa-Yaa-Zaa, in which Xaa is preferably Ala or Leu, Yaa is preferably Ala or Tyr, and Zaa is preferably Ala, but then cleaves at a variable distance from the C-terminus. A typical cleavage is -Ala-Ala-|-Arg-Ala-Ala-Lys-Glu-Asn-Tyr-Ala-Leu-Ala-Ala.; EC=3.4.21.102;
DNA Binding
EC Number 3.4.21.102
Enzyme Function FUNCTION: Cleavage of the 16 C-terminal residues from the D1 precursor of photosystem II (PSII). This proteolytic processing is necessary to allow the light-driven assembly of the oxygen-evolving cluster (a tetranuclear manganese), which is responsible for photosynthetic water oxidation. {ECO:0000250|UniProtKB:Q55669}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (3); Chain (1); Domain (1); Frameshift (1); Signal peptide (1)
Keywords Hydrolase;Protease;Reference proteome;Serine protease;Signal;Thylakoid
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cellular thylakoid lumen {ECO:0000250|UniProtKB:O04073}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..29; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 45,575
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda