Detail Information for IndEnz0002019309
IED ID IndEnz0002019309
Enzyme Type ID protease019309
Protein Name Probable dipeptidyl-aminopeptidase B
DPAP B
EC 3.4.14.5
Gene Name DAPB MGG_07745
Organism Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Pyricularia oryzae)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta sordariomyceta Sordariomycetes Sordariomycetidae Magnaporthales Pyriculariaceae Pyricularia Magnaporthe oryzae (Rice blast fungus) (Pyricularia oryzae) Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Pyricularia oryzae)
Enzyme Sequence MPVDKKSGNGRPSLDSVSSISTTSIVFDHLNDLEIHKKHRPHLMTESIRRDDHLSDFDDDDPLKQEMDGEGDLETGPFLAGRDAYTFGGGKYMDRKFRRIMIVVAGLLVAAWVGGLFVYIASKSYKHATTVEHDPEKTKAAALTSGKKITMDQVRSGTWYAASHDITWIAGPKGEDGLMIEVGADGKDYIVIEDGRAENPDSSAEAEVDVTASRRTLMKNGSFRYQGRMHIPSGAEPSRDQQKVLLRTEQKSNWRHSHTACYWIWDVATETAEPLIPASPDARVQNAQWSPTSDAIVFTRENNLYLRTIGSKKVTQITKDGGADLFYGVPDWVYEEEVIAGASTTWWSEDGKYVAFLRTNETGVPAFPVQYFMSRPSGASPKAGEETYPEVRDIKYPRSGSHNPVVDVQFYDIARGDVFTVDINGGFADEDRLITTVLWAGSQVIVKETNRVSDIMRVVLIDVKKRTGKTTRTVDVGKIDGGWFEISQNTKYIPADPKKGRDQDGYIDTVIHNDGDHLAYFSPPDNPDPIMLTSGPGWEVVDAPSAVDLENNLVYFIATKEGSTQRHVYSVQLDGKNMKSFTDTEAKGYYDVSFSSGAGYALLSYKGPKIPWQKVVSTPANNQRYEVLIEENKELAESARKYDLPLLNYGTLNVEGVELNYLERRPPQFSEKKKYPVLFHQYSGPGSQSVSQKFSVDFQSYVAASLGYIVVTFDGRGTGFIGRKNRVLVRSRLGEIEAQDQIAAAKHWASLGYVDPSRIAIWGWSYGGFQTLKTLEADAGRTFSYGMAVAPVTDWRFYDSIYTERYMLTPQQNEDGYTKSAVHNVSALASNKRFLLMHGASDDNVHFQNSLTLLDKLDMGAVENYDVHVFPDSDHSIFFHNANKIIYDKLENWLVNAFNGEWLKVNNAKPVELVHPTQLVREREKAKLRKRWQEIQNK
Enzyme Length 938
Uniprot Accession Number A4QYQ5
Absorption
Active Site ACT_SITE 765; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 842; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 875; /note=Charge relay system; /evidence=ECO:0000250
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline.; EC=3.4.14.5;
DNA Binding
EC Number 3.4.14.5
Enzyme Function FUNCTION: Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (3); Chain (1); Glycosylation (3); Topological domain (2); Transmembrane (1)
Keywords Aminopeptidase;Glycoprotein;Hydrolase;Membrane;Protease;Reference proteome;Serine protease;Signal-anchor;Transmembrane;Transmembrane helix;Vacuole
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Note=Lysosome-like vacuoles. {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 105,281
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda