Detail Information for IndEnz0002019318
IED ID IndEnz0002019318
Enzyme Type ID protease019318
Protein Name Cystatin
Gene Name
Organism Tropidechis carinatus (Australian rough-scaled snake)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Sauropsida Sauria (diapsids) Lepidosauria (lepidosaurs) Squamata (squamates) Bifurcata (split-tongued squamates) Unidentata Episquamata Toxicofera Serpentes (snakes) Colubroidea Elapidae Notechinae Tropidechis Tropidechis carinatus (Australian rough-scaled snake)
Enzyme Sequence MVHSQLPVAAPLRLLCALLLLPSATMIPGGLYPRSVTDPDVQEAAECAVQEYNALSANAYYYKQLRIVEAQSQVVTGAKYYLTMELMKTKCAKTTGKPKVYKEIQNCELPPKAQQEKLTCHFQVWSRPWLQKIELTKMSCN
Enzyme Length 141
Uniprot Accession Number E3P6N9
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Inhibits various C1 cysteine proteases including cathepsin L, papain and cathepsin B. This protein has no toxic activity and its function in the venom is unknown. It may play a role as a housekeeping or regulatory protein (By similarity). {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Disulfide bond (2); Domain (1); Motif (1); Signal peptide (1); Site (1)
Keywords Disulfide bond;Protease inhibitor;Secreted;Signal;Thiol protease inhibitor
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..26; /evidence=ECO:0000250
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif MOTIF 73..77; /note=Secondary area of contact; /evidence=ECO:0000250
Gene Encoded By
Mass 15,895
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda