Detail Information for IndEnz0002019323
IED ID IndEnz0002019323
Enzyme Type ID protease019323
Protein Name Putative dipeptidase CPSG_01350
EC 3.4.13.19
Gene Name CPSG_01350
Organism Coccidioides posadasii (strain RMSCC 757 / Silveira) (Valley fever fungus)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Onygenales incertae sedis Coccidioides Coccidioides posadasii (Valley fever fungus) Coccidioides posadasii (strain RMSCC 757 / Silveira) (Valley fever fungus)
Enzyme Sequence MSARDNEKGSARSQPSHAAASEIENVPRPSRQQSWTGTMIKVFIICACAGIVSKYIIPLDSIFKSVHIDPHDYATRANRILSTTPLIDGHNDLPYLIRLETKNKIYDHEKLPFRTGLLSHTDQIKIQEGKLGGQFWSVFVECATDPNAEIDDPTWAVRDTLEQIDVTKRLVQEYPDLLEYCESASCAKAAFKRGKVGSFLGIEGGHQIGNSLASLRQVYDLGVRYITVTHNCDNAFATAASTVAVGKPDLGLTDFGREFVKEMNRLGMLVDLSHVSHQTMRDILSVTKAPVMFSHSSSYALSKHLRNVPDDVLNGVTKNGGVVMVTFVPSFLKVDDPASATIHDAVDHILHVAKVAGWDHVGIGSDFDGTADVPEGLENVSKYPRLIELLLERGVTDEQARKLIGENILRVWSNVEEIAENIRALGEKPNEETWSGRKWTAAIDIPMPFMFKDSADKRKEL
Enzyme Length 461
Uniprot Accession Number E9CV02
Absorption
Active Site
Activity Regulation
Binding Site BINDING 230; /note=Substrate; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073; BINDING 306; /note=Substrate; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073; BINDING 366; /note=Substrate; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid; Xref=Rhea:RHEA:48940, ChEBI:CHEBI:15377, ChEBI:CHEBI:59869, ChEBI:CHEBI:77460; EC=3.4.13.19; Evidence={ECO:0000255|PROSITE-ProRule:PRU10073};
DNA Binding
EC Number 3.4.13.19
Enzyme Function FUNCTION: Hydrolyzes a wide range of dipeptides. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Binding site (3); Chain (1); Disulfide bond (1); Glycosylation (1); Metal binding (6); Region (1); Transmembrane (1)
Keywords Dipeptidase;Disulfide bond;Glycoprotein;Hydrolase;Membrane;Metal-binding;Metalloprotease;Protease;Reference proteome;Transmembrane;Transmembrane helix;Zinc
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 51,063
Kinetics
Metal Binding METAL 90; /note=Zinc 1; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073; METAL 92; /note=Zinc 1; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073; METAL 203; /note=Zinc 1; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073; METAL 203; /note=Zinc 2; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073; METAL 274; /note=Zinc 2; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073; METAL 295; /note=Zinc 2; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10073
Rhea ID RHEA:48940
Cross Reference Brenda