| IED ID | IndEnz0002019340 |
| Enzyme Type ID | protease019340 |
| Protein Name |
Alliumin Fragment |
| Gene Name | |
| Organism | Allium sativum (Garlic) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae Liliopsida Petrosaviidae Asparagales Amaryllidaceae Allioideae Allieae Allium Allium sativum (Garlic) |
| Enzyme Sequence | DDFLCAGGCL |
| Enzyme Length | 10 |
| Uniprot Accession Number | P84796 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Has antifungal activity against M.arachidicola with an IC(50) of 1.3 uM, but not against F.oxysporum. Has antibacterial activity against the Gram-negative bacterium P.fluorescens. No antibacterial activity against the Gram-positive bacteria B.subtilis, B.cereus and B.megaterium, or against the Gram-negative bacterium E.coli. Has antiproliferative activity towards L1210 leukemia cells with an IC(50) of 8.33 uM, but lacks antiproliferative activity towards HepG2 hepatoma cells. Lacks mitogenic towards murine splenocytes. Lacks ribonuclease activity towards yeast tRNA and protease activity towards casein. {ECO:0000269|PubMed:15629528}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Non-terminal residue (1) |
| Keywords | Antibiotic;Antimicrobial;Direct protein sequencing;Fungicide |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 1,013 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |