Detail Information for IndEnz0002019352
IED ID IndEnz0002019352
Enzyme Type ID protease019352
Protein Name Putative zinc protease AlbF
EC 3.4.24.-
Antilisterial bacteriocin subtilosin biosynthesis protein AlbF
Gene Name albF ywhN BSU37420
Organism Bacillus subtilis (strain 168)
Taxonomic Lineage cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Bacillales Bacillaceae Bacillus Bacillus subtilis group Bacillus subtilis Bacillus subtilis subsp. subtilis Bacillus subtilis (strain 168)
Enzyme Sequence MEKKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFGSRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMFTSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLSPSSPAAVFPAGRIEDIEALDISDLQKAYKAAYQAHRMTLFLIGGSENTETLLPPHLQLEKRPDYHAERKIIPACPPVLSQKMMLGDEERMEDTWTGLQIGALPGQNDLLSIKLYWDIAARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYVTQKKEQVAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQVFLSLIDAMASSNKAIIHVSQKEAIRQ
Enzyme Length 426
Uniprot Accession Number P71006
Absorption
Active Site ACT_SITE 69; /note=Proton acceptor; /evidence=ECO:0000250
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.24.-
Enzyme Function FUNCTION: Required for production of the bacteriocin subtilosin. Could catalyze some step in the processing of presubtilosin. {ECO:0000269|PubMed:10572140, ECO:0000269|PubMed:10809709}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Metal binding (3)
Keywords Antibiotic biosynthesis;Bacteriocin biosynthesis;Hydrolase;Metal-binding;Metalloprotease;Protease;Reference proteome;Zinc
Interact With
Induction INDUCTION: Transcription is highly induced by oxygen limitation and is under dual and independent control of Spo0A-AbrB and ResDE. {ECO:0000269|PubMed:10809710}.
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 21630458;
Motif
Gene Encoded By
Mass 48,982
Kinetics
Metal Binding METAL 66; /note=Zinc; /evidence=ECO:0000250; METAL 70; /note=Zinc; /evidence=ECO:0000250; METAL 142; /note=Zinc; /evidence=ECO:0000250
Rhea ID
Cross Reference Brenda