Detail Information for IndEnz0002019375
IED ID IndEnz0002019375
Enzyme Type ID protease019375
Protein Name Zingipain-1
EC 3.4.22.67
Cysteine proteinase GP-I
Gene Name
Organism Zingiber officinale (Ginger) (Amomum zingiber)
Taxonomic Lineage cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae Liliopsida Petrosaviidae commelinids Zingiberales Zingiberaceae Zingiber Zingiber officinale (Ginger) (Amomum zingiber)
Enzyme Sequence DVLPDSIDWREKGAVVPVKNQGGCGSCWAFDAIAAVEGINQIVTGDLISLSEQQLVDCSTRNHGCEGGWPYRAFQYIINNGGINSEEHYPYTGTNGTCDTKENAHVVSIDSYRNVPSNDEKSLQKAVANQPVSVTMDAAGRDFQLYRNGIFTGSCNISANHYRTVGGRETENDKDYWTVKNSWGKNWGESGYIRVERNIAESSGKCGIAISPSYPIKEXXX
Enzyme Length 221
Uniprot Accession Number P82473
Absorption
Active Site ACT_SITE 27; /evidence=ECO:0000255|PROSITE-ProRule:PRU10090; ACT_SITE 161; /evidence=ECO:0000255|PROSITE-ProRule:PRU10090
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Preferential cleavage of peptides with a proline residue at the P2 position.; EC=3.4.22.67;
DNA Binding
EC Number 3.4.22.67
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Disulfide bond (3); Glycosylation (2); Sequence caution (1); Sequence uncertainty (1)
Keywords Direct protein sequencing;Disulfide bond;Glycoprotein;Hydrolase;Protease;Thiol protease
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 24,244
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda