Detail Information for IndEnz0002019384
IED ID IndEnz0002019384
Enzyme Type ID protease019384
Protein Name Short tail fiber protein gp12
Gene product 12
gp12
Gene Name 12
Organism Enterobacteria phage T4 (Bacteriophage T4)
Taxonomic Lineage Viruses Duplodnaviria Heunggongvirae Uroviricota Caudoviricetes Caudovirales Myoviridae (phages with contractile tails) Tevenvirinae Tequatrovirus Enterobacteria phage T4 (Bacteriophage T4)
Enzyme Sequence MSNNTYQHVSNESRYVKFDPTDTNFPPEITDVQAAIAAISPAGVNGVPDASSTTKGILFIPTEQEVIDGTNNTKAVTPATLATRLSYPNATETVYGLTRYSTNDEAIAGVNNESSITPAKFTVALNNAFETRVSTESSNGVIKISSLPQALAGADDTTAMTPLKTQQLAIKLIAQIAPSETTATESDQGVVQLATVAQVRQGTLREGYAISPYTFMNSSSTEEYKGVIKLGTQSEVNSNNASVAVTGATLNGRGSTTSMRGVVKLTTTAGSQSGGDASSALAWNADVIQQRGGQIIYGTLRIEDTFTIANGGANITGTVRMTGGYIQGNRIVTQNEIDRTIPVGAIMMWAADSLPSDAWRFCHGGTVSASDCPLYASRIGTRYGGNPSNPGLPDMRGLFVRGSGRGSHLTNPNVNGNDQFGKPRLGVGCTGGYVGEVQIQQMSYHKHAGGFGEHDDLGAFGNTRRSNFVGTRKGLDWDNRSYFTNDGYEIDPESQRNSKYTLNRPELIGNETRPWNISLNYIIKVKE
Enzyme Length 527
Uniprot Accession Number P10930
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Structural component of the short tail fiber. Adhesion protein that binds irreversibly to the lipopolysaccharides component (LPS) on the cell surface of Escherichia coli B strains during virus attachment. After at least three long tail fibers have bound, short tail fibers extend and bind irreversibly to the core region of the host cell LPS. {ECO:0000269|PubMed:12837775, ECO:0000269|PubMed:27193680}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Beta strand (11); Chain (1); Helix (7); Sequence conflict (2); Turn (3)
Keywords 3D-structure;Host-virus interaction;Late protein;Reference proteome;Viral attachment to host cell;Viral attachment to host entry receptor;Viral tail fiber protein;Viral tail protein;Virion;Virus entry into host cell
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Virion {ECO:0000269|PubMed:27193680}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D Electron microscopy (2); X-ray crystallography (2)
Cross Reference PDB 1H6W; 1OCY; 1PDI; 5IV5;
Mapped Pubmed ID 10504409; 10782996; 11530935; 12888344; 12923574;
Motif
Gene Encoded By
Mass 56,205
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda