IED ID | IndEnz0002019394 |
Enzyme Type ID | protease019394 |
Protein Name |
Antimicrobial peptide eNAP-2 Fragment |
Gene Name | |
Organism | Equus caballus (Horse) |
Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Laurasiatheria Perissodactyla (odd-toed ungulates) Equidae (horses) Equus Equus Equus caballus (Horse) |
Enzyme Sequence | EVERKHPLGGSRPGRCPTVPPGTFGHCACLCTGDASEPKGQKCCSN |
Enzyme Length | 46 |
Uniprot Accession Number | P56928 |
Absorption | |
Active Site | |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | |
DNA Binding | |
EC Number | |
Enzyme Function | FUNCTION: Has antibiotic activity against several equine uterine pathogens; S.zooepidemicus, E.coli and P.aeruginosa. Highly efficient against S.zoopedemicus. Not active against K.pneumoniae. Selectively inactivates microbial serine proteases (subtilisin A and proteinase K) without inhibiting mammalian serine proteases (human neutrophil elastase, human cathepsin G and bovine pancreatic trypsin). |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Chain (1); Domain (1); Non-terminal residue (1) |
Keywords | Antibiotic;Antimicrobial;Direct protein sequencing;Protease inhibitor;Reference proteome |
Interact With | |
Induction | |
Subcellular Location | |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | - |
Motif | |
Gene Encoded By | |
Mass | 4,769 |
Kinetics | |
Metal Binding | |
Rhea ID | |
Cross Reference Brenda |