Detail Information for IndEnz0004000046
IED ID IndEnz0004000046
Enzyme Type ID xylanase000046
Protein Name Ethylene-responsive transcription factor 2
NtERF2
Ethylene-responsive element-binding factor 2
EREBP-2
Gene Name ERF2 ERF-2
Organism Nicotiana tabacum (Common tobacco)
Taxonomic Lineage cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae asterids lamiids Solanales Solanaceae Nicotianoideae Nicotianeae Nicotiana Nicotiana tabacum (Common tobacco)
Enzyme Sequence MYQPISTELPPTSFSSLMPCLTDTWGDLPLKVDDSEDMVIYGLLSDALTAGWTPFNLTSTEIKAEPREEIEPATIPVPSVAPPAETTTAQAVVPKGRHYRGVRQRPWGKFAAEIRDPAKNGARVWLGTYETAEEAALAYDKAAYRMRGSKALLNFPHRIGLNEPEPVRLTAKRRSPEPASSSISSALENGSPKRRRKAVAAKKAELEVQSRSNAMQVGCQMEQFPVGEQLLVS
Enzyme Length 233
Uniprot Accession Number Q40479
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding DNA_BIND 98..156; /note=AP2/ERF; /evidence=ECO:0000255|PROSITE-ProRule:PRU00366
EC Number
Enzyme Function FUNCTION: Acts as a transcriptional activator and may be involved in disease resistance pathways. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways mediated by ethylene, that seems to depend on a protein kinase cascade, and to be influenced by methyl-jasmonate. {ECO:0000269|PubMed:10652129, ECO:0000269|PubMed:10792818, ECO:0000269|PubMed:7756828, ECO:0000269|Ref.2}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Compositional bias (1); DNA binding (1); Region (1)
Keywords Activator;DNA-binding;Ethylene signaling pathway;Nucleus;Plant defense;Reference proteome;Transcription;Transcription regulation
Interact With
Induction INDUCTION: Induced by ethephon (ethylene-releasing compound) in buds and to a lower extent in leaves. Strongly induced by cycloheximide and mechanical stimuli. Wounding leads to a both local and systemic expression, independently of ethylene, and through a de-novo-protein-synthesis-independent regulation. Wound induction is reduced by methyl-jasmonate. Induction by purified xylanase from Trichoderma viride (TvX) and another elicitor from Phytophthora infestans (PiE), that appears to be mediated by both protein kinases and protein phosphatases. {ECO:0000269|PubMed:10652129, ECO:0000269|PubMed:12090623, ECO:0000269|PubMed:7756828, ECO:0000269|Ref.2}.
Subcellular Location SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00366, ECO:0000269|PubMed:10792818}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 16452120;
Motif
Gene Encoded By
Mass 25,563
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda