IED ID | IndEnz0004000048 |
Enzyme Type ID | xylanase000048 |
Protein Name |
Endoglucanase A EC 3.2.1.4 Cellulase A Endo-1,4-beta-glucanase A EGA Endo-1,4-beta-xylanase EC 3.2.1.8 |
Gene Name | celA |
Organism | Ruminococcus albus |
Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Firmicutes Clostridia Eubacteriales Oscillospiraceae Ruminococcus Ruminococcus albus |
Enzyme Sequence | MRKPDKDADRLTTLDLARSGEVRDISAMELVGEMKTGWNLGNSLDATGAPGNASEVNWGNPKTTKEMIDAVYNKGFDVIRIPVTWGGHVGDAPDYKIDDEWIARVQEVVNYAYDDGAYVIINSHHEEDWRIPDNEHIDAVDEKTAAIWKQVAERFKDYGDHLIFEGLNEPRVKGSPQEWNGGTEEGRRCVDRLNKTFLDTVRATGGNNEKRLLLMTTYASSSMSNVIKDTAIPEDDHIGFSIHAYTPYAFTYNANADWELFHWDDSHDGELVSLMTNLKENYLDKDIPVIITEYGAVNKDNNDEDRAKWVSSYIEYAELLGGIPCVWWDNGYYSSGNELFGIFDRNTCTWFTDTVTDAIIENAK |
Enzyme Length | 364 |
Uniprot Accession Number | P23660 |
Absorption | |
Active Site | ACT_SITE 169; /note=Proton donor; /evidence=ECO:0000250; ACT_SITE 293; /note=Nucleophile; /evidence=ECO:0000250 |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | CATALYTIC ACTIVITY: Reaction=Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.; EC=3.2.1.4; CATALYTIC ACTIVITY: Reaction=Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.; EC=3.2.1.8; |
DNA Binding | |
EC Number | 3.2.1.4; 3.2.1.8 |
Enzyme Function | FUNCTION: Hydrolyzes both carboxymethylcellulose and xylan. Probably has a role in hydrolyzing oligosaccharides derived from cellulose, which are transported across the cell wall. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Active site (2); Chain (1) |
Keywords | Carbohydrate metabolism;Cellulose degradation;Cytoplasm;Direct protein sequencing;Glycosidase;Hydrolase;Polysaccharide degradation;Xylan degradation |
Interact With | |
Induction | |
Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}. |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | - |
Motif | |
Gene Encoded By | |
Mass | 41,218 |
Kinetics | |
Metal Binding | |
Rhea ID | |
Cross Reference Brenda |