| IED ID | IndEnz0004000065 |
| Enzyme Type ID | xylanase000065 |
| Protein Name |
Xylanolytic transcriptional activator xlnR Xylanase regulator |
| Gene Name | xlnR AN7610 |
| Organism | Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Nidulantes Emericella nidulans (Aspergillus nidulans) Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) |
| Enzyme Sequence | MSTTSLQQFATATSFSPFSNSQSARMSQSQSQTIGLDTLAEGSQYVLEQLQLSREGGNSENNSTFKPSSVRDSLAEARSMIRKNSSSAPVRRRISRACDQCNQLRTKCDGQNPCAHCIEFGLTCEYARERKKRGKASKKDIAAAAAAAGHQGGMGNRSPTDRRLSQEPGGRYDSVLEASRVQSHLPANGLSSIHNTQAAHSQPPLGSALDALHLNHFTQLNESGRSQMPVSDLRSLQILHNNPRSPSALPHGLNAYNDNTFSLLNSQEPNTTSLNHFRLGNSTDNPSAQFLGLSPPAQSPGWLPLPSPSPANFPSFPMAPFSGTSLRYPVLQPVLPHIASIIPQSLACDLLDLYFTSSSSSHLSPQSPYVVGYIFRKQSFLHPTKPRVCSPGLLASMLWVGAQTSDAPFLTSPPSARGRVCQKLLELTIGLLRPLIHGPALGEASPNYAANMVINGVALGGFGVSMDQLGAQSTATGAVDDVATYVHLATVVSASEYKAASMRWWTAAWSLARELKLGRELPPNASQPGQDGERENEGDNPSKRNQSLHGGNSNVNVTEEEREERRRLWWLLYATDRHLALCYNRPLTLLDKECSQLLQPMNDDLWQAGDFPAATYRAVGPPIECTGHSMFGYFLPLMTILGGIIDLQQAREHPRYGLTFRSGPDLDQYIMAITQQLDAYGQSLKDFEARYINSLALAENEPPENPHIDHLSPSGRSSSTVGSRVNESIVHTKMVVAYGTHIMHVLYVLLAGKWDPINLLEDHDMWISSESFLAAMSHAVGAAEAAADILEYDPDLSFMPFFFGIYLLQGSFLLLLAADKLQGDANPSVVRACETIVRAHEACVVTLNTEYQRTFRKVMRSALAQVRGRVPDDFGEQQQRRREVLSLYRWTGDGTGLALS |
| Enzyme Length | 900 |
| Uniprot Accession Number | Q5AVS0 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | DNA_BIND 98..124; /note=Zn(2)-C6 fungal-type; /evidence=ECO:0000255|PROSITE-ProRule:PRU00227 |
| EC Number | |
| Enzyme Function | FUNCTION: Transcriptional activator of the xylanolytic system. Involved in the regulation of extracellular cellulolytic and xylanolytic genes and in the regulation of the intracellular activities of D-xylose catabolic genes in the pentose catabolic pathway (PCP) in response to the presence of D-xylose. Binds to the DNA sequence 5'-GGNTAAA-3'. {ECO:0000269|PubMed:18332432, ECO:0000269|PubMed:18420433, ECO:0000269|PubMed:21484208}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Compositional bias (1); DNA binding (1); Erroneous initiation (2); Frameshift (1); Region (4); Sequence conflict (1) |
| Keywords | Activator;DNA-binding;Metal-binding;Nucleus;Reference proteome;Transcription;Transcription regulation;Zinc |
| Interact With | |
| Induction | INDUCTION: Expressed in presence of xylose. Repressed in presence of glucose through the action of the creA transcription repressor. {ECO:0000269|PubMed:18332432, ECO:0000269|PubMed:18420433}. |
| Subcellular Location | SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 98,441 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |