| IED ID | IndEnz0004000176 |
| Enzyme Type ID | xylanase000176 |
| Protein Name |
Endo-1,4-beta-xylanase Xylanase EC 3.2.1.8 1,4-beta-D-xylan xylanohydrolase |
| Gene Name | xlnA |
| Organism | Niallia circulans (Bacillus circulans) |
| Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Bacillales Bacillaceae Niallia Niallia circulans (Bacillus circulans) |
| Enzyme Sequence | MFKFKKNFLVGLSAALMSISLFSATASAASTDYWQNWTDGGGIVNAVNGSGGNYSVNWSNTGNFVVGKGWTTGSPFRTINYNAGVWAPNGNGYLTLYGWTRSPLIEYYVVDSWGTYRPTGTYKGTVKSDGGTYDIYTTTRYNAPSIDGDRTTFTQYWSVRQSKRPTGSNATITFTNHVNAWKSHGMNLGSNWAYQVMATEGYQSSGSSNVTVW |
| Enzyme Length | 213 |
| Uniprot Accession Number | P09850 |
| Absorption | |
| Active Site | ACT_SITE 106; /note="Nucleophile"; /evidence="ECO:0000255|PROSITE-ProRule:PRU10062, ECO:0000269|PubMed:8019418"; ACT_SITE 200; /note="Proton donor"; /evidence="ECO:0000255|PROSITE-ProRule:PRU10063, ECO:0000269|PubMed:8019418" |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.; EC=3.2.1.8; |
| DNA Binding | |
| EC Number | 3.2.1.8 |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | PATHWAY: Glycan degradation; xylan degradation. |
| nucleotide Binding | |
| Features | Active site (2); Beta strand (14); Chain (1); Domain (1); Helix (1); Signal peptide (1); Turn (1) |
| Keywords | 3D-structure;Carbohydrate metabolism;Glycosidase;Hydrolase;Polysaccharide degradation;Signal;Xylan degradation |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..28 |
| Structure 3D | X-ray crystallography (16) |
| Cross Reference PDB | 1BCX; 1BVV; 1C5H; 1C5I; 1HV0; 1HV1; 1XNB; 1XNC; 2BVV; 3LB9; 3VZJ; 3VZK; 3VZL; 3VZM; 3VZN; 3VZO; |
| Mapped Pubmed ID | 10220321; 10860737; 11513590; 20163191; 23578322; 7700870; |
| Motif | |
| Gene Encoded By | |
| Mass | 23,359 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda | 3.2.1.8; |