Detail Information for IndEnz0004000218
IED ID IndEnz0004000218
Enzyme Type ID xylanase000218
Protein Name Endo-1,4-beta-xylanase
Xylanase
EC 3.2.1.8
1,4-beta-D-xylan xylanohydrolase
TAXI
Gene Name XYNA
Organism Thermoascus aurantiacus
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Thermoascaceae Thermoascus Thermoascus aurantiacus
Enzyme Sequence MVRPTILLTSLLLAPFAAASPILEERQAAQSVDQLIKARGKVYFGVATDQNRLTTGKNAAIIQADFGQVTPENSMKWDATEPSQGNFNFAGADYLVNWAQQNGKLIRGHTLVWHSQLPSWVSSITDKNTLTNVMKNHITTLMTRYKGKIRAWDVVNEAFNEDGSLRQTVFLNVIGEDYIPIAFQTARAADPNAKLYINDYNLDSASYPKTQAIVNRVKQWRAAGVPIDGIGSQTHLSAGQGAGVLQALPLLASAGTPEVAITELDVAGASPTDYVNVVNACLNVQSCVGITVWGVADPDSWRASTTPLLFDGNFNPKPAYNAIVQDLQQ
Enzyme Length 329
Uniprot Accession Number P23360
Absorption
Active Site ACT_SITE 157; /note=Proton donor; ACT_SITE 263; /note=Nucleophile
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.; EC=3.2.1.8;
DNA Binding
EC Number 3.2.1.8
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Beta strand (12); Chain (1); Disulfide bond (1); Domain (1); Helix (16); Modified residue (1); Sequence caution (2); Sequence conflict (4); Signal peptide (1); Turn (3)
Keywords 3D-structure;Carbohydrate metabolism;Direct protein sequencing;Disulfide bond;Glycosidase;Hydrolase;Polysaccharide degradation;Pyrrolidone carboxylic acid;Signal;Xylan degradation
Interact With
Induction
Subcellular Location
Modified Residue MOD_RES 27; /note=Pyrrolidone carboxylic acid; /evidence=ECO:0000250|UniProtKB:P56588
Post Translational Modification
Signal Peptide SIGNAL 1..26; /evidence="ECO:0000269|PubMed:11223515, ECO:0000269|PubMed:1924265, ECO:0000269|Ref.2"
Structure 3D X-ray crystallography (36)
Cross Reference PDB 1GOK; 1GOM; 1GOO; 1GOQ; 1GOR; 1I1W; 1I1X; 1K6A; 1TUX; 2BNJ; 3NYD; 3O2L; 4BS0; 5RG4; 5RG5; 5RG6; 5RG7; 5RG8; 5RG9; 5RGA; 5RGB; 5RGC; 5RGD; 5RGE; 5RGF; 7K4P; 7K4Q; 7K4R; 7K4S; 7K4T; 7K4U; 7K4V; 7K4W; 7K4X; 7K4Y; 7K4Z;
Mapped Pubmed ID 10329194; 11741607; 12499546; 16140328; 22357762; 24132235; 32968058; 33214289; 9649746;
Motif
Gene Encoded By
Mass 35,686
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda 3.2.1.8;