| IED ID | IndEnz0004000218 |
| Enzyme Type ID | xylanase000218 |
| Protein Name |
Endo-1,4-beta-xylanase Xylanase EC 3.2.1.8 1,4-beta-D-xylan xylanohydrolase TAXI |
| Gene Name | XYNA |
| Organism | Thermoascus aurantiacus |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Thermoascaceae Thermoascus Thermoascus aurantiacus |
| Enzyme Sequence | MVRPTILLTSLLLAPFAAASPILEERQAAQSVDQLIKARGKVYFGVATDQNRLTTGKNAAIIQADFGQVTPENSMKWDATEPSQGNFNFAGADYLVNWAQQNGKLIRGHTLVWHSQLPSWVSSITDKNTLTNVMKNHITTLMTRYKGKIRAWDVVNEAFNEDGSLRQTVFLNVIGEDYIPIAFQTARAADPNAKLYINDYNLDSASYPKTQAIVNRVKQWRAAGVPIDGIGSQTHLSAGQGAGVLQALPLLASAGTPEVAITELDVAGASPTDYVNVVNACLNVQSCVGITVWGVADPDSWRASTTPLLFDGNFNPKPAYNAIVQDLQQ |
| Enzyme Length | 329 |
| Uniprot Accession Number | P23360 |
| Absorption | |
| Active Site | ACT_SITE 157; /note=Proton donor; ACT_SITE 263; /note=Nucleophile |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.; EC=3.2.1.8; |
| DNA Binding | |
| EC Number | 3.2.1.8 |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Beta strand (12); Chain (1); Disulfide bond (1); Domain (1); Helix (16); Modified residue (1); Sequence caution (2); Sequence conflict (4); Signal peptide (1); Turn (3) |
| Keywords | 3D-structure;Carbohydrate metabolism;Direct protein sequencing;Disulfide bond;Glycosidase;Hydrolase;Polysaccharide degradation;Pyrrolidone carboxylic acid;Signal;Xylan degradation |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | MOD_RES 27; /note=Pyrrolidone carboxylic acid; /evidence=ECO:0000250|UniProtKB:P56588 |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..26; /evidence="ECO:0000269|PubMed:11223515, ECO:0000269|PubMed:1924265, ECO:0000269|Ref.2" |
| Structure 3D | X-ray crystallography (36) |
| Cross Reference PDB | 1GOK; 1GOM; 1GOO; 1GOQ; 1GOR; 1I1W; 1I1X; 1K6A; 1TUX; 2BNJ; 3NYD; 3O2L; 4BS0; 5RG4; 5RG5; 5RG6; 5RG7; 5RG8; 5RG9; 5RGA; 5RGB; 5RGC; 5RGD; 5RGE; 5RGF; 7K4P; 7K4Q; 7K4R; 7K4S; 7K4T; 7K4U; 7K4V; 7K4W; 7K4X; 7K4Y; 7K4Z; |
| Mapped Pubmed ID | 10329194; 11741607; 12499546; 16140328; 22357762; 24132235; 32968058; 33214289; 9649746; |
| Motif | |
| Gene Encoded By | |
| Mass | 35,686 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda | 3.2.1.8; |