| IED ID | IndEnz0004000246 |
| Enzyme Type ID | xylanase000246 |
| Protein Name |
Xylanolytic transcriptional activator xlnR Xylanase regulator |
| Gene Name | xlnR |
| Organism | Aspergillus niger |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Circumdati Aspergillus niger |
| Enzyme Sequence | MSTPSIPQFTSSFSPFSSGSHSTGMAPSQTVGLDTLAEGSQYVLEQLQLSRDAAGTGAGDGATSTSLRNSMSHTKDQPPFDNEKNQSTGSGFRDALQRDPLVEARSAVRKTSSSAPVRRRISRACDQCNQLRTKCDGQHPCAHCIEFGLTCEYARERKKRGKASKKDLAAAAAAATQGSNGHSGQANASLMGERTSEDSRPGQDVNGTYDSAFESHHLSSQPSHMQHASTAGISGLHESQTAPSHSQSSLGTTIDAMHLNHFNTMNDSGRPAMSISDLRSLPPSVLPPQGLSSGYNASAFALVNPQEPGSPANQFRLGSSAENPTAPFLGLSPPGQSPGWLPLPSPSPANFPSFSLHPFSSTLRYPVLQPVLPHIASIIPQSLACDLLDVYFTSSSSSHLSPLSPYVVGYIFRKQSFLHPTKPRICSPGLLASMLWVAAQTSEAAFLTSPPSARGRVCQKLLELTIGLLRPLVHGPATGEASPNYAANMVINGVALGGFGVSMDQLGAQSSATGAVDDVATYVHLATVVSASEYKAASMRWWTAAWSLARELKLGRELPPNVSHARQDGERDGDGEADKRHPPTLITSLGHGSGSSGINVTEEEREERRRLWWLLYATDRHLALCYNRPLTLLDKECGGLLQPMNDDLWQVGDFAAAAYRQVGPPVECTGHSMYGYFLPLMTILGGIVDLHHAENHPRFGLAFRNSPEWERQVLDVTRQLDTYGRSLKEFEARYTSNLTLGATDNEPVVEGAHLDHTSPSGRSSSTVGSRVSESIVHTRMVVAYGTHIMHVLHILLAGKWDPVNLLEDHDLWISSESFVSAMSHAVGAAEAAAEILEYDPDLSFMPFFFGIYLLQGSFLLLLAADKLQGDASPSVVRACETIVRAHEACVVTLNTEYQRTFRKVMRSALAQVRGRIPEDFGEQQQRRREVLALYRWSGDGSGLAL |
| Enzyme Length | 945 |
| Uniprot Accession Number | O42804 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | DNA_BIND 125..151; /note=Zn(2)-C6 fungal-type; /evidence=ECO:0000255|PROSITE-ProRule:PRU00227 |
| EC Number | |
| Enzyme Function | FUNCTION: Transcriptional activator of the xylanolytic system. Involved in the regulation of extracellular cellulolytic and xylanolytic genes and in the regulation of the intracellular activities of D-xylose catabolic genes in the pentose catabolic pathway (PCP) in response to the presence of D-xylose. Binds to the DNA sequence 5'-GGNTAAA-3'. {ECO:0000269|PubMed:10508057, ECO:0000269|PubMed:10760176, ECO:0000269|PubMed:11916668, ECO:0000269|PubMed:12242504, ECO:0000269|PubMed:17951513, ECO:0000269|PubMed:18332432, ECO:0000269|PubMed:21484208, ECO:0000269|PubMed:21892241, ECO:0000269|PubMed:9758775, ECO:0000269|Ref.8}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Compositional bias (3); DNA binding (1); Frameshift (1); Region (4) |
| Keywords | Activator;DNA-binding;Metal-binding;Nucleus;Transcription;Transcription regulation;Zinc |
| Interact With | |
| Induction | INDUCTION: Expressed in presence of xylose. {ECO:0000269|PubMed:18332432}. |
| Subcellular Location | SUBCELLULAR LOCATION: Nucleus. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 102,073 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |