| IED ID |
IndEnz0005000071 |
| Enzyme Type ID |
lipase000071 |
| Protein Name |
Neurotactin
|
| Gene Name |
Nrt CG9704 |
| Organism |
Drosophila melanogaster (Fruit fly) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Metazoa
Eumetazoa
Bilateria
Protostomia
Ecdysozoa
Panarthropoda
Arthropoda
Mandibulata
Pancrustacea
Hexapoda
Insecta
Dicondylia
Pterygota (winged insects)
Neoptera
Endopterygota
Diptera
Brachycera
Muscomorpha
Eremoneura
Cyclorrhapha
Schizophora
Acalyptratae
Ephydroidea
Drosophilidae (pomace flies)
Drosophilinae
Drosophilini
Drosophila (fruit flies)
Sophophora
melanogaster group
melanogaster subgroup
Drosophila melanogaster (Fruit fly)
|
| Enzyme Sequence |
MGELEEKETPPTETTAAQQEALEEPKETDKMLDKKEDAKEKTPSPQTSKPASPNAGKKSSPVAEKKIDDAELAKSKSGNGEEIIDIPAENGTKPDSADDKKISKEEREVKPKKIPIGGLKLPGFFMKNKPKADGDGAEGELLEKEKEEDKDKEANGDAATGSGKDEQKSRPGLGERLRSFFARKPSAEKEKKQLVNGDADAKSEATAEATPAEDASDAPPKRGLLNAIKLPIANMIPKKKSNDDVELGLGKAGLASMETLDDSLKDQDTVDRAPVKTNGTEELKGELKDEKLAAEEKLAAEEEEQNRPVSLLTRLRGYKCSVDDALIVFGILLFVLLLGVIGYVLTHETLTSPPLREGRYIMAVTGCGPVEGVKEDGAFAFRGIPYAKPPVDRLRWKPAELIDDINMCWNDTLQTHNSSVVCTQRLGNGTTVGDEDCLYLDVVTPHVRYNNPLPVVVLIGAESLAGPSPGILRPSARYSRSHDVIFVRPNFRLGVFGFLALDALTKEAHPPTSGNYALTDIIAVLNWIKLNIVHFGGDPQSVTLLGHRAGATLVTLLVNSQKVKGLYTRAWASSGSAILPGKPLSESGKQNEQLMATLECADIQCLREASSERLWAATPDTWLHFPVDLPQPQEANASGSRHEWLVLDGDVVFEHPSDTWKREQANDKPVLVMGATAHEAHTEKLRELHANWTREEVRAYLENSQIGALGLTDEVIEKYNASSYASLVSIISDIRSVCPLLTNARQQPSVPFYVVTQGEGPDQLATVDADVQAILGRYEPHTVEQRRFVSAMQQLFYYYVSHGTVQSFVQNRRVINVGQDAQPEEDYLPCNYWISKDIVPRYARVD |
| Enzyme Length |
846 |
| Uniprot Accession Number |
P23654 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: May mediate or modulate cell adhesion between embryonic cells during development. {ECO:0000269|PubMed:2100266, ECO:0000269|PubMed:2120047, ECO:0000269|PubMed:2120048}. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Compositional bias (5); Disulfide bond (3); Glycosylation (6); Modified residue (17); Region (1); Sequence conflict (3); Topological domain (2); Transmembrane (1) |
| Keywords |
Cell adhesion;Disulfide bond;Glycoprotein;Membrane;Phosphoprotein;Reference proteome;Signal-anchor;Transmembrane;Transmembrane helix |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Membrane {ECO:0000269|PubMed:2100266, ECO:0000269|PubMed:2120047}; Single-pass type II membrane protein {ECO:0000269|PubMed:2100266, ECO:0000269|PubMed:2120047}. Note=Expressed in membranes during embryogenesis. |
| Modified Residue |
MOD_RES 28; /note=Phosphothreonine; by PKC; /evidence=ECO:0000255; MOD_RES 42; /note=Phosphothreonine; /evidence=ECO:0000269|PubMed:18327897; MOD_RES 44; /note=Phosphoserine; /evidence=ECO:0000269|PubMed:18327897; MOD_RES 47; /note=Phosphothreonine; /evidence=ECO:0000269|PubMed:18327897; MOD_RES 48; /note=Phosphoserine; /evidence=ECO:0000269|PubMed:18327897; MOD_RES 52; /note=Phosphoserine; /evidence=ECO:0000269|PubMed:18327897; MOD_RES 75; /note=Phosphoserine; by PKC; /evidence=ECO:0000255; MOD_RES 77; /note=Phosphoserine; /evidence=ECO:0000269|PubMed:18327897; MOD_RES 103; /note=Phosphoserine; by PKC; /evidence=ECO:0000255; MOD_RES 169; /note=Phosphoserine; by PKC; /evidence=ECO:0000255; MOD_RES 186; /note=Phosphoserine; /evidence=ECO:0000255; MOD_RES 203; /note=Phosphoserine; /evidence=ECO:0000269|PubMed:18327897; MOD_RES 206; /note=Phosphothreonine; /evidence=ECO:0000269|PubMed:18327897; MOD_RES 256; /note=Phosphoserine; /evidence=ECO:0000269|PubMed:18327897; MOD_RES 259; /note=Phosphothreonine; /evidence=ECO:0000269|PubMed:18327897; MOD_RES 263; /note=Phosphoserine; /evidence=ECO:0000269|PubMed:18327897; MOD_RES 269; /note=Phosphothreonine; /evidence=ECO:0000269|PubMed:18327897 |
| Post Translational Modification |
|
| Signal Peptide |
|
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
10322452;
10352022;
10390152;
10470487;
10518988;
10557205;
10562554;
10580988;
10591654;
10688207;
10798396;
10806097;
10822259;
10850494;
10896146;
10908580;
10953008;
10970840;
10995441;
11076958;
11163263;
11171404;
11223034;
11231123;
11486054;
11700298;
11740560;
11748148;
11756472;
11782316;
11900973;
11970887;
11970893;
12095613;
12135929;
12163402;
12351791;
12386932;
12408803;
12421699;
12441301;
12467587;
12510194;
12526793;
12586063;
12655063;
12711540;
12781133;
12781136;
12783792;
12874119;
12900457;
12925708;
1295746;
14523402;
14588240;
14605208;
1482114;
14981094;
15030758;
15055200;
15084280;
15128660;
15252125;
15252443;
15261673;
15268881;
15302858;
15385958;
15454540;
15459108;
15556867;
15572139;
15617679;
15710747;
15723789;
15743877;
15930114;
15985179;
16123312;
16228011;
16455680;
16481356;
16516189;
16580994;
16616121;
16624855;
16707805;
16814731;
16818611;
16862128;
16934003;
17011486;
17038518;
17070515;
17113384;
17156430;
17202187;
17314131;
17573340;
17660572;
17698923;
17785526;
17881487;
17912601;
17942486;
18041774;
18073442;
1820686;
18445681;
18585373;
18931655;
18938249;
19064670;
19232093;
19270173;
19317464;
19538956;
19567473;
1957349;
19646433;
19711412;
19772636;
19789180;
19864461;
19890324;
19934015;
20003348;
20069381;
20184661;
20194639;
20220848;
20519528;
20533357;
20630948;
20861518;
21074052;
21177962;
2118870;
21253006;
21558369;
21565181;
21613323;
21613546;
21708145;
2175256;
2188361;
21945234;
21986496;
22036477;
22073214;
22132223;
22293958;
22575490;
23063363;
23070853;
23071443;
23178937;
23326246;
23618231;
23658195;
23850873;
23872236;
23880429;
23902690;
23951546;
24292889;
24681004;
24755291;
2502313;
25193493;
25286318;
25358341;
25687947;
25715730;
26141956;
26451484;
26460970;
26568309;
26818071;
27015425;
27058248;
27350102;
27582081;
27683892;
27794539;
29618587;
29670218;
30705102;
32576111;
32815271;
32848200;
32900993;
33028960;
33234716;
33555999;
33563972;
33749594;
33798197;
34228708;
7527841;
7680635;
7707975;
7958919;
8647396;
8798144;
8878684;
8890157;
8945511;
8994828;
9151682;
9335485;
9459435;
9491984;
9581760;
9657150;
9671493;
9729490;
9926937;
9927420;
|
| Motif |
|
| Gene Encoded By |
|
| Mass |
92,776 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
|